Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency

Akifumi Endo, Ken Watanabe, Tamae Oe, Kyoko Suzuki, Tomoyo Matsubara, Norio Shimizu, Hiroki Kurahashi, Tetsushi Yoshikawa, Harutaka Katano, Naoki Inoue, Kohsuke Imai, Masatoshi Takagi, Tomohiro Morio, Shuki Mizutani

Research output: Contribution to journalArticle

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Abstract

It has been unclear whether chromosomally integrated human herpesvirus 6 (ciHHV-6) can be activated with pathogenic effects on the human body. We present molecular and virological evidence of ciHHV-6A activation in a patient with X-linked severe combined immunodeficiency. These findings have significant implications for the management of patients with ciHHV-6.

Original languageEnglish
Pages (from-to)545-548
Number of pages4
JournalClinical Infectious Diseases
Volume59
Issue number4
DOIs
Publication statusPublished - 15-08-2014

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X-Linked Combined Immunodeficiency Diseases
Human Herpesvirus 6
Virus Activation
Human Body

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Endo, Akifumi ; Watanabe, Ken ; Oe, Tamae ; Suzuki, Kyoko ; Matsubara, Tomoyo ; Shimizu, Norio ; Kurahashi, Hiroki ; Yoshikawa, Tetsushi ; Katano, Harutaka ; Inoue, Naoki ; Imai, Kohsuke ; Takagi, Masatoshi ; Morio, Tomohiro ; Mizutani, Shuki. / Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency. In: Clinical Infectious Diseases. 2014 ; Vol. 59, No. 4. pp. 545-548.
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Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency. / Endo, Akifumi; Watanabe, Ken; Oe, Tamae; Suzuki, Kyoko; Matsubara, Tomoyo; Shimizu, Norio; Kurahashi, Hiroki; Yoshikawa, Tetsushi; Katano, Harutaka; Inoue, Naoki; Imai, Kohsuke; Takagi, Masatoshi; Morio, Tomohiro; Mizutani, Shuki.

In: Clinical Infectious Diseases, Vol. 59, No. 4, 15.08.2014, p. 545-548.

Research output: Contribution to journalArticle

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AU - Morio, Tomohiro

AU - Mizutani, Shuki

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