Molecular characterization of clinical carbapenem-resistant Enterobacterales from Qatar

Fatma Ben Abid; Clement K.M. Tsui; Yohei Doi; Anand Deshmukh; Christi L. McElheny; William C. Bachman; Erin L. Fowler; Ahmed Albishawi; Kamran Mushtaq; Emad B. Ibrahim; Sanjay H. Doiphode; Manal M. Hamed; Muna A. Almaslmani; Abdullatif Alkhal; Adeel A. Butt; Ali S. Omrani

doi:10.1007/s10096-021-04185-7

Molecular characterization of clinical carbapenem-resistant Enterobacterales from Qatar

Fatma Ben Abid
, Clement K.M. Tsui
, Yohei Doi
, Anand Deshmukh
, Christi L. McElheny
, William C. Bachman
, Erin L. Fowler
, Ahmed Albishawi
, Kamran Mushtaq
, Emad B. Ibrahim
, Sanjay H. Doiphode
, Manal M. Hamed
, Muna A. Almaslmani
, Abdullatif Alkhal
, Adeel A. Butt
, Ali S. Omrani

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

One hundred forty-nine carbapenem-resistant Enterobacterales from clinical samples obtained between April 2014 and November 2017 were subjected to whole genome sequencing and multi-locus sequence typing. Klebsiella pneumoniae (81, 54.4%) and Escherichia coli (38, 25.5%) were the most common species. Genes encoding metallo-β-lactamases were detected in 68 (45.8%) isolates, and OXA-48-like enzymes in 60 (40.3%). bla_NDM-1 (45; 30.2%) and bla_OXA-48 (29; 19.5%) were the most frequent. KPC-encoding genes were identified in 5 (3.6%) isolates. Most common sequence types were E. coli ST410 (8; 21.1%) and ST38 (7; 18.4%), and K. pneumoniae ST147 (13; 16%) and ST231 (7; 8.6%).

Original language	English
Pages (from-to)	1779-1785
Number of pages	7
Journal	European Journal of Clinical Microbiology and Infectious Diseases
Volume	40
Issue number	8
DOIs	https://doi.org/10.1007/s10096-021-04185-7
Publication status	Published - 08-2021
Externally published	Yes

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10096-021-04185-7

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Abid, F. B., Tsui, C. K. M., Doi, Y., Deshmukh, A., McElheny, C. L., Bachman, W. C., Fowler, E. L., Albishawi, A., Mushtaq, K., Ibrahim, E. B., Doiphode, S. H., Hamed, M. M., Almaslmani, M. A., Alkhal, A., Butt, A. A., & Omrani, A. S. (2021). Molecular characterization of clinical carbapenem-resistant Enterobacterales from Qatar. European Journal of Clinical Microbiology and Infectious Diseases, 40(8), 1779-1785. https://doi.org/10.1007/s10096-021-04185-7

@article{3cc206a70805463ba7f49ca2676d6836,

title = "Molecular characterization of clinical carbapenem-resistant Enterobacterales from Qatar",

abstract = "One hundred forty-nine carbapenem-resistant Enterobacterales from clinical samples obtained between April 2014 and November 2017 were subjected to whole genome sequencing and multi-locus sequence typing. Klebsiella pneumoniae (81, 54.4\%) and Escherichia coli (38, 25.5\%) were the most common species. Genes encoding metallo-β-lactamases were detected in 68 (45.8\%) isolates, and OXA-48-like enzymes in 60 (40.3\%). blaNDM-1 (45; 30.2\%) and blaOXA-48 (29; 19.5\%) were the most frequent. KPC-encoding genes were identified in 5 (3.6\%) isolates. Most common sequence types were E. coli ST410 (8; 21.1\%) and ST38 (7; 18.4\%), and K. pneumoniae ST147 (13; 16\%) and ST231 (7; 8.6\%).",

author = "Abid, \{Fatma Ben\} and Tsui, \{Clement K.M.\} and Yohei Doi and Anand Deshmukh and McElheny, \{Christi L.\} and Bachman, \{William C.\} and Fowler, \{Erin L.\} and Ahmed Albishawi and Kamran Mushtaq and Ibrahim, \{Emad B.\} and Doiphode, \{Sanjay H.\} and Hamed, \{Manal M.\} and Almaslmani, \{Muna A.\} and Abdullatif Alkhal and Butt, \{Adeel A.\} and Omrani, \{Ali S.\}",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",

year = "2021",

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doi = "10.1007/s10096-021-04185-7",

language = "English",

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Abid, FB, Tsui, CKM, Doi, Y, Deshmukh, A, McElheny, CL, Bachman, WC, Fowler, EL, Albishawi, A, Mushtaq, K, Ibrahim, EB, Doiphode, SH, Hamed, MM, Almaslmani, MA, Alkhal, A, Butt, AA & Omrani, AS 2021, 'Molecular characterization of clinical carbapenem-resistant Enterobacterales from Qatar', European Journal of Clinical Microbiology and Infectious Diseases, vol. 40, no. 8, pp. 1779-1785. https://doi.org/10.1007/s10096-021-04185-7

TY - JOUR

T1 - Molecular characterization of clinical carbapenem-resistant Enterobacterales from Qatar

AU - Abid, Fatma Ben

AU - Tsui, Clement K.M.

AU - Doi, Yohei

AU - Deshmukh, Anand

AU - McElheny, Christi L.

AU - Bachman, William C.

AU - Fowler, Erin L.

AU - Albishawi, Ahmed

AU - Mushtaq, Kamran

AU - Ibrahim, Emad B.

AU - Doiphode, Sanjay H.

AU - Hamed, Manal M.

AU - Almaslmani, Muna A.

AU - Alkhal, Abdullatif

AU - Butt, Adeel A.

AU - Omrani, Ali S.

PY - 2021/8

Y1 - 2021/8

N2 - One hundred forty-nine carbapenem-resistant Enterobacterales from clinical samples obtained between April 2014 and November 2017 were subjected to whole genome sequencing and multi-locus sequence typing. Klebsiella pneumoniae (81, 54.4%) and Escherichia coli (38, 25.5%) were the most common species. Genes encoding metallo-β-lactamases were detected in 68 (45.8%) isolates, and OXA-48-like enzymes in 60 (40.3%). blaNDM-1 (45; 30.2%) and blaOXA-48 (29; 19.5%) were the most frequent. KPC-encoding genes were identified in 5 (3.6%) isolates. Most common sequence types were E. coli ST410 (8; 21.1%) and ST38 (7; 18.4%), and K. pneumoniae ST147 (13; 16%) and ST231 (7; 8.6%).

AB - One hundred forty-nine carbapenem-resistant Enterobacterales from clinical samples obtained between April 2014 and November 2017 were subjected to whole genome sequencing and multi-locus sequence typing. Klebsiella pneumoniae (81, 54.4%) and Escherichia coli (38, 25.5%) were the most common species. Genes encoding metallo-β-lactamases were detected in 68 (45.8%) isolates, and OXA-48-like enzymes in 60 (40.3%). blaNDM-1 (45; 30.2%) and blaOXA-48 (29; 19.5%) were the most frequent. KPC-encoding genes were identified in 5 (3.6%) isolates. Most common sequence types were E. coli ST410 (8; 21.1%) and ST38 (7; 18.4%), and K. pneumoniae ST147 (13; 16%) and ST231 (7; 8.6%).

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VL - 40

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JO - European Journal of Clinical Microbiology and Infectious Diseases

JF - European Journal of Clinical Microbiology and Infectious Diseases

IS - 8

ER -

Molecular characterization of clinical carbapenem-resistant Enterobacterales from Qatar

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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