Molecular features of community-associated extended-spectrum-β-lactamase-producing Escherichia coli strains in the United States

Fupin Hu, Jessica A. O'Hara, Jesabel I. Rivera, Yohei Doi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We characterized 30 community-associated extended-spectrum-β-lactamase-producing Escherichia coli isolates collected from five hospitals in the United States. Nineteen sequence types were identified. All sequence type 131 (ST131) isolates had the fimH30 allele. IncFII-FIA-FIB was the most common replicon type among the blaCTX-M-carrying plasmids, followed by IncFII-FIA and IncA/C. Restriction analysis of the IncFII-FIA-FIB and IncFII-FIA plasmids yielded related profiles for plasmids originating from different hospitals. The plasmids containing blaCTX-M or blaSHV were stably maintained after serial passages.

Original languageEnglish
Pages (from-to)6953-6957
Number of pages5
JournalAntimicrobial agents and chemotherapy
Volume58
Issue number11
DOIs
Publication statusPublished - 01-11-2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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