Molecular mechanism of alpha-herpesvirus proliferation

T. Murata, Y. Nishiyama

Research output: Contribution to journalReview article


Among members of the subfamily alpha herpesviruses, herpes simplex virus (HSV) is one of the most well-studied and the most important human pathogen. HSV is reported to possess the large, double-stranded DNA genome which contains at least 80 genes. Recent studies have revealed the functions and roles of many gene products in HSV-infected cells. This article briefly reviews the results of these studies relating to HSV replication mechanism in cells and latent infection in central nerve system (CNS).

Original languageEnglish
Pages (from-to)773-778
Number of pages6
JournalNippon rinsho. Japanese journal of clinical medicine
Issue number4
Publication statusPublished - 04-2000


All Science Journal Classification (ASJC) codes

  • Medicine(all)

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