TY - JOUR
T1 - Multi-institutional retrospective analysis of learning curves on dosimetry and operation time before and after introduction of intraoperatively built custom-linked seeds in prostate brachytherapy
AU - Ishiyama, Hiromichi
AU - Satoh, Takefumi
AU - Yorozu, Atsunori
AU - Saito, Shiro
AU - Kataoka, Masaaki
AU - Hashine, Katsuyoshi
AU - Nakamura, Ryuji
AU - Tanji, Susumu
AU - Masui, Koji
AU - Okihara, Koji
AU - Ohashi, Toshio
AU - Momma, Tetsuo
AU - Aoki, Manabu
AU - Miki, Kenta
AU - Kato, Masako
AU - Morita, Masashi
AU - Katayama, Norihisa
AU - Nasu, Yasutomo
AU - Kawanaka, Takashi
AU - Fukumori, Tomoharu
AU - Ito, Fumitaka
AU - Shiroki, Ryoichi
AU - Baba, Yuji
AU - Inadome, Akito
AU - Yoshioka, Yasuo
AU - Takayama, Hitoshi
AU - Hayakawa, Kazushige
N1 - Publisher Copyright:
© 2015 The Author 2015.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - This multi-institutional retrospective analysis examined learning curves for dosimetric parameters and operation time after introduction of intraoperatively built custom-linked (IBCL) seeds. Data from consecutive patients treated with seed implantation before and after introduction of IBCL seeds (loose seed, n = 428; IBCL seed, n = 426) were collected from 13 centers. Dose-volume histogram parameters, operation times, and seed migration rates were compared before and after introduction of IBCL seeds. At the 1-month CT analysis, no significant differences were seen in dose to 90% of prostate volume between before and after IBCL seed introduction. No learning curve for dosimetry was seen. Prostate and rectal volume receiving at least 150% of prescription dose (V150 and RV150) were higher in the loose-seed group than in the IBCL-seed group. Operation time was extended by up to 10 min when IBCL seeds were used, although there was a short learning curve of about five patients. The percentage of patients with seed migration in the IBCL-seed group was one-tenth that in the loose-seed group. Our study revealed no dosimetric demerits, no learning curve for dosimetry, and a slightly extended operation time for IBCL seeds. A significant reduction in the rate of seed migration was identified in the IBCL-seed group.
AB - This multi-institutional retrospective analysis examined learning curves for dosimetric parameters and operation time after introduction of intraoperatively built custom-linked (IBCL) seeds. Data from consecutive patients treated with seed implantation before and after introduction of IBCL seeds (loose seed, n = 428; IBCL seed, n = 426) were collected from 13 centers. Dose-volume histogram parameters, operation times, and seed migration rates were compared before and after introduction of IBCL seeds. At the 1-month CT analysis, no significant differences were seen in dose to 90% of prostate volume between before and after IBCL seed introduction. No learning curve for dosimetry was seen. Prostate and rectal volume receiving at least 150% of prescription dose (V150 and RV150) were higher in the loose-seed group than in the IBCL-seed group. Operation time was extended by up to 10 min when IBCL seeds were used, although there was a short learning curve of about five patients. The percentage of patients with seed migration in the IBCL-seed group was one-tenth that in the loose-seed group. Our study revealed no dosimetric demerits, no learning curve for dosimetry, and a slightly extended operation time for IBCL seeds. A significant reduction in the rate of seed migration was identified in the IBCL-seed group.
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U2 - 10.1093/jrr/rrv065
DO - 10.1093/jrr/rrv065
M3 - Article
C2 - 26494116
AN - SCOPUS:84959863886
SN - 0449-3060
VL - 57
SP - 68
EP - 74
JO - Journal of Radiation Research
JF - Journal of Radiation Research
IS - 1
ER -