Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum β-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil

Doroti De Oliveira Garcia, Yohei Doi, Dora Szabo, Jennifer M. Adams-Haduch, Tânia M.I. Vaz, Daniela Leite, Maria Clara Padoveze, Maristela P. Freire, Fernanda P. Silveira, David L. Paterson

Research output: Contribution to journalArticlepeer-review

53 Citations (Scopus)

Abstract

An outbreak of cephalosporin-resistant Klebsiella pneumoniae occurred in a neonatal intensive care unit in São Paulo, Brazil. Of the 10 pulsotypes identified during the outbreak and follow-up periods, nine produced CTX-M-2 or its new variant CTX-M-59 and one produced SHV-5. blaCTX-M-2/59 genes were located on closely related plasmids that were transferable.

Original languageEnglish
Pages (from-to)1790-1793
Number of pages4
JournalAntimicrobial agents and chemotherapy
Volume52
Issue number5
DOIs
Publication statusPublished - 05-2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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