TY - JOUR
T1 - Multifocal primary melanoma of the cervical spinal cord successfully treated by tumorectomy
T2 - a case report
AU - Iga, Takahito
AU - Iwanami, Akio
AU - Funakoshi, Takeru
AU - Mikami, Shuji
AU - Tsuji, Osahiko
AU - Nagoshi, Narihito
AU - Okada, Eijiro
AU - Fujita, Nobuyuki
AU - Yagi, Mitsuru
AU - Watanabe, Kota
AU - Nakamura, Masaya
AU - Matsumoto, Morio
N1 - Publisher Copyright:
© International Spinal Cord Society 2018.
PY - 2018
Y1 - 2018
N2 - Introduction Multifocal primary melanoma of the spine is extremely rare. Here, we report a case of multifocal primary melanoma of the cervical spinal cord. Case presentation A 39-year-old man presented with a 1-year history of numbness of the upper extremities and back. Magnetic resonance imaging of the cervical spine suggested multifocal intradural extramedullary tumors at levels C2 and C4–C5. A diagnostic biopsy revealed a pathological diagnosis of malignant melanoma. Tumorectomy was then performed. The numbness in the patient’s upper extremities improved, and he was discharged. As of 2 years after surgery, no signs of local or systemic recurrence have been noted. Discussion Primary melanoma of the spinal cord usually carries a poor prognosis. However, in this case, the outcome following tumorectomy has been highly favorable. We speculate that this is because the MIB-1 labeling index of the tumors was less than 1%.
AB - Introduction Multifocal primary melanoma of the spine is extremely rare. Here, we report a case of multifocal primary melanoma of the cervical spinal cord. Case presentation A 39-year-old man presented with a 1-year history of numbness of the upper extremities and back. Magnetic resonance imaging of the cervical spine suggested multifocal intradural extramedullary tumors at levels C2 and C4–C5. A diagnostic biopsy revealed a pathological diagnosis of malignant melanoma. Tumorectomy was then performed. The numbness in the patient’s upper extremities improved, and he was discharged. As of 2 years after surgery, no signs of local or systemic recurrence have been noted. Discussion Primary melanoma of the spinal cord usually carries a poor prognosis. However, in this case, the outcome following tumorectomy has been highly favorable. We speculate that this is because the MIB-1 labeling index of the tumors was less than 1%.
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U2 - 10.1038/s41394-018-0063-x
DO - 10.1038/s41394-018-0063-x
M3 - Article
AN - SCOPUS:85069946468
SN - 2058-6124
VL - 4
JO - Spinal Cord Series and Cases
JF - Spinal Cord Series and Cases
M1 - 24
ER -