Neuronal polarity: From extracellular signals to intracellular mechanisms

Nariko Arimura, Kozo Kaibuchi

Research output: Contribution to journalReview articlepeer-review

517 Citations (Scopus)


After they are born and differentiate, neurons break their previous symmetry, dramatically change their shape, and establish two structurally and functionally distinct compartments - axons and dendrites - within one cell. How do neurons develop their morphologically and molecularly distinct compartments? Recent studies have implicated several signalling pathways evoked by extracellular signals as having essential roles in a number of aspects of neuronal polarization.

Original languageEnglish
Pages (from-to)194-205
Number of pages12
JournalNature Reviews Neuroscience
Issue number3
Publication statusPublished - 03-2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Neuroscience


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