Neuroprotective effects of magnesium on cerebral ischemia and cerebral contusion

Takeshi Enomoto, Yukihiro Noda, Toshitaka Nabeshima

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Neuroprotective effects of magnesium (Mg(2+)) have been shown in experimental studies by using animal models of the cerebral ischemia and cerebral contusion. We review the neuroprotective effects of Mg(2+) in the histological and behavioral studies. In the animal models of cerebral ischemia, Mg(2+) treatment reduces the infarct volume, inhibits the neuronal death, and attenuates the motor impairments. In the animal models of cerebral contusion, Mg(2+) treatment inhibits the neuronal death and edema, and attenuates not only the motor impairments but also cognitive dysfunction.

Original languageEnglish
Pages (from-to)60-64
Number of pages5
JournalClinical calcium
Volume14
Issue number8
Publication statusPublished - 08-2004

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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  • Cite this

    Enomoto, T., Noda, Y., & Nabeshima, T. (2004). Neuroprotective effects of magnesium on cerebral ischemia and cerebral contusion. Clinical calcium, 14(8), 60-64.