Neuroprotective effects of magnesium on cerebral ischemia and cerebral contusion

Takeshi Enomoto, Yukihiro Noda, Toshitaka Nabeshima

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Neuroprotective effects of magnesium (Mg(2+)) have been shown in experimental studies by using animal models of the cerebral ischemia and cerebral contusion. We review the neuroprotective effects of Mg(2+) in the histological and behavioral studies. In the animal models of cerebral ischemia, Mg(2+) treatment reduces the infarct volume, inhibits the neuronal death, and attenuates the motor impairments. In the animal models of cerebral contusion, Mg(2+) treatment inhibits the neuronal death and edema, and attenuates not only the motor impairments but also cognitive dysfunction.

Original languageEnglish
Pages (from-to)60-64
Number of pages5
JournalClinical calcium
Volume14
Issue number8
Publication statusPublished - 01-01-2004
Externally publishedYes

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Neuroprotective Agents
Brain Ischemia
Magnesium
Animal Models
Edema
Brain Contusion

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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Neuroprotective effects of magnesium on cerebral ischemia and cerebral contusion. / Enomoto, Takeshi; Noda, Yukihiro; Nabeshima, Toshitaka.

In: Clinical calcium, Vol. 14, No. 8, 01.01.2004, p. 60-64.

Research output: Contribution to journalReview article

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