Neutralizing antibody assay for human Herpesvirus‐6

Sadao Suga; Tetsushi Yoshikawa; Yoshizo Asano; Takehiko Yazaki; Takao Ozaki

doi:10.1002/jmv.1890300104

Neutralizing antibody assay for human Herpesvirus‐6

Sadao Suga, Tetsushi Yoshikawa, Yoshizo Asano, Takehiko Yazaki, Takao Ozaki

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

Antibody to human herpesvirus‐6 (HHV‐6) was measured in cord blood mononuclear cell cultures by a neutralization (NT) test, in which the presence or absence of characteristic large cell formation in cells infected with HHV‐6 was used as an indicator for neutralization of the virus. The NT test could measure antibodies during and just after the appearance of the skin rash in patients with exanthem subitum. The levels of antibodies measured by the NT test was generally higher than that by an indirect immunofluorescence assay.

Original language	English
Pages (from-to)	14-19
Number of pages	6
Journal	Journal of Medical Virology
Volume	30
Issue number	1
DOIs	https://doi.org/10.1002/jmv.1890300104
Publication status	Published - 01-1990
Externally published	Yes

All Science Journal Classification (ASJC) codes

Virology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/jmv.1890300104

Cite this

@article{7dff6873372a4d5fa83711815b7553e8,

title = "Neutralizing antibody assay for human Herpesvirus‐6",

abstract = "Antibody to human herpesvirus‐6 (HHV‐6) was measured in cord blood mononuclear cell cultures by a neutralization (NT) test, in which the presence or absence of characteristic large cell formation in cells infected with HHV‐6 was used as an indicator for neutralization of the virus. The NT test could measure antibodies during and just after the appearance of the skin rash in patients with exanthem subitum. The levels of antibodies measured by the NT test was generally higher than that by an indirect immunofluorescence assay.",

author = "Sadao Suga and Tetsushi Yoshikawa and Yoshizo Asano and Takehiko Yazaki and Takao Ozaki",

year = "1990",

month = jan,

doi = "10.1002/jmv.1890300104",

language = "English",

volume = "30",

pages = "14--19",

journal = "Journal of Medical Virology",

issn = "0146-6615",

publisher = "John Wiley and Sons Inc.",

number = "1",

}

TY - JOUR

T1 - Neutralizing antibody assay for human Herpesvirus‐6

AU - Suga, Sadao

AU - Yoshikawa, Tetsushi

AU - Asano, Yoshizo

AU - Yazaki, Takehiko

AU - Ozaki, Takao

PY - 1990/1

Y1 - 1990/1

N2 - Antibody to human herpesvirus‐6 (HHV‐6) was measured in cord blood mononuclear cell cultures by a neutralization (NT) test, in which the presence or absence of characteristic large cell formation in cells infected with HHV‐6 was used as an indicator for neutralization of the virus. The NT test could measure antibodies during and just after the appearance of the skin rash in patients with exanthem subitum. The levels of antibodies measured by the NT test was generally higher than that by an indirect immunofluorescence assay.

AB - Antibody to human herpesvirus‐6 (HHV‐6) was measured in cord blood mononuclear cell cultures by a neutralization (NT) test, in which the presence or absence of characteristic large cell formation in cells infected with HHV‐6 was used as an indicator for neutralization of the virus. The NT test could measure antibodies during and just after the appearance of the skin rash in patients with exanthem subitum. The levels of antibodies measured by the NT test was generally higher than that by an indirect immunofluorescence assay.

UR - http://www.scopus.com/inward/record.url?scp=0025129142&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025129142&partnerID=8YFLogxK

U2 - 10.1002/jmv.1890300104

DO - 10.1002/jmv.1890300104

M3 - Article

C2 - 2406371

AN - SCOPUS:0025129142

SN - 0146-6615

VL - 30

SP - 14

EP - 19

JO - Journal of Medical Virology

JF - Journal of Medical Virology

IS - 1

ER -

Neutralizing antibody assay for human Herpesvirus‐6

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this