Neutralizing antibody assay for human Herpesvirus‐6

Sadao Suga, Tetsushi Yoshikawa, Yoshizo Asano, Takehiko Yazaki, Takao Ozaki

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Abstract

Antibody to human herpesvirus‐6 (HHV‐6) was measured in cord blood mononuclear cell cultures by a neutralization (NT) test, in which the presence or absence of characteristic large cell formation in cells infected with HHV‐6 was used as an indicator for neutralization of the virus. The NT test could measure antibodies during and just after the appearance of the skin rash in patients with exanthem subitum. The levels of antibodies measured by the NT test was generally higher than that by an indirect immunofluorescence assay.

Original languageEnglish
Pages (from-to)14-19
Number of pages6
JournalJournal of Medical Virology
Volume30
Issue number1
DOIs
Publication statusPublished - 01-1990

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All Science Journal Classification (ASJC) codes

  • Virology
  • Infectious Diseases

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