Neutralizing antibody assay for human Herpesvirus‐6

Sadao Suga, Tetsushi Yoshikawa, Yoshizo Asano, Takehiko Yazaki, Takao Ozaki

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Antibody to human herpesvirus‐6 (HHV‐6) was measured in cord blood mononuclear cell cultures by a neutralization (NT) test, in which the presence or absence of characteristic large cell formation in cells infected with HHV‐6 was used as an indicator for neutralization of the virus. The NT test could measure antibodies during and just after the appearance of the skin rash in patients with exanthem subitum. The levels of antibodies measured by the NT test was generally higher than that by an indirect immunofluorescence assay.

Original languageEnglish
Pages (from-to)14-19
Number of pages6
JournalJournal of Medical Virology
Volume30
Issue number1
DOIs
Publication statusPublished - 01-01-1990

Fingerprint

Neutralization Tests
Neutralizing Antibodies
Exanthema
Cell-in-Cell Formation
Antibodies
Indirect Fluorescent Antibody Technique
Fetal Blood
Blood Cells
Cell Culture Techniques
Viruses

All Science Journal Classification (ASJC) codes

  • Infectious Diseases
  • Virology

Cite this

Suga, Sadao ; Yoshikawa, Tetsushi ; Asano, Yoshizo ; Yazaki, Takehiko ; Ozaki, Takao. / Neutralizing antibody assay for human Herpesvirus‐6. In: Journal of Medical Virology. 1990 ; Vol. 30, No. 1. pp. 14-19.
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Neutralizing antibody assay for human Herpesvirus‐6. / Suga, Sadao; Yoshikawa, Tetsushi; Asano, Yoshizo; Yazaki, Takehiko; Ozaki, Takao.

In: Journal of Medical Virology, Vol. 30, No. 1, 01.01.1990, p. 14-19.

Research output: Contribution to journalArticle

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