New findings, pathophysiology, and antigen analysis in pollen-food allergy syndrome

Akiko Yagami, Motohiro Ebisawa

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

PURPOSE OF REVIEW: PFAS shows various cross-reactivities with antigens because of the area in which the patient resides and dietary habits, and progress in component allergen analysis in recent years has clarified the pathogenesis. This review describes newly identified findings for antigens involved in PFAS. RECENT FINDINGS: We describe recent findings for PR-10 family, profilin and LTP, as known major antigens for PFAS. Microarrays of allergen components have significantly improved the ability to describe IgE profiles. In addition, we describe a new antigen, GRP, in the fruit pulp of recently identified fruit. SUMMARY: PFAS is a food allergy based on the cross-reactivity of pollen antigens and food antigens. Symptoms induced by sensitization differ depending on the specific antigen. The functions of each antigen are diverse, and even the same antigen can cause different symptoms. As analytical techniques progress, the findings will help to establish treatments, such as specific immunotherapy.

Original languageEnglish
Pages (from-to)218-223
Number of pages6
JournalCurrent opinion in allergy and clinical immunology
Volume19
Issue number3
DOIs
Publication statusPublished - 01-06-2019

Fingerprint

Seasonal Allergic Rhinitis
Food Hypersensitivity
Antigens
Allergens
Fruit
Profilins
Aptitude
Feeding Behavior
Pollen
Immunotherapy
Immunoglobulin E
Food

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

Cite this

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New findings, pathophysiology, and antigen analysis in pollen-food allergy syndrome. / Yagami, Akiko; Ebisawa, Motohiro.

In: Current opinion in allergy and clinical immunology, Vol. 19, No. 3, 01.06.2019, p. 218-223.

Research output: Contribution to journalArticle

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