New reduced volume preparation regimen in colon capsule endoscopy

Yasuo Kakugawa, Yutaka Saito, Shoichi Saito, Kenji Watanabe, Naoki Omiya, Mitsuyuki Murano, Shiro Oka, Tetsuo Arakawa, Hidemi Goto, Kazuhide Higuchi, Shinji Tanaka, Hideki Ishikawa, Hisao Tajiri

Research output: Contribution to journalReview article

38 Citations (Scopus)

Abstract

AIM: To evaluate the effectiveness of our proposed bowel preparation method for colon capsule endoscopy. METHODS: A pilot, multicenter, randomized controlled trial compared our proposed "reduced volume method" (group A) with the "conventional volume method" (group B) preparation regimens. Group A did not drink polyethylene glycol electrolyte lavage solution (PEGELS) the day before the capsule procedure, while group B drank 2 L. During the procedure day, groups A and B drank 2 L and 1 L of PEG-ELS, respectively, and swallowed the colon capsule (PillCam COLON® capsule). Two hours later the first booster of 100 g magnesium citrate mixed with 900 mL water was administered to both groups, and the second booster was administered six hours post capsule ingestion as long as the capsule had not been excreted by that time. Capsule videos were reviewed for grading of cleansing level. RESULTS: Sixty-four subjects were enrolled, with results from 60 analyzed. Groups A and B included 31 and 29 subjects, respectively. Twenty-nine (94%) subjects in group A and 25 (86%) subjects in group B had adequate bowel preparation (ns). Twenty-two (71%) of the 31 subjects in group A excreted the capsule within its battery life compared to 16 (55%) of the 29 subjects in group B (ns). Of the remaining 22 subjects whose capsules were not excreted within the battery life, all of the capsules reached the left side colon before they stopped functioning. A single adverse event was reported in one subject who had mild symptoms of nausea and vomiting one hour after starting to drink PEG-ELS, due to ingesting the PEG-ELS faster than recommended. CONCLUSION: Our proposed reduced volume bowel preparation method for colon capsule without PEG-ELS during the days before the procedure was as effective as the conventional volume method.

Original languageEnglish
Pages (from-to)2092-2098
Number of pages7
JournalWorld Journal of Gastroenterology
Volume18
Issue number17
DOIs
Publication statusPublished - 07-05-2012
Externally publishedYes

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Capsule Endoscopy
Capsules
Colon
Therapeutic Irrigation
Nausea
Electrolytes
Vomiting
Randomized Controlled Trials
Eating

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Kakugawa, Y., Saito, Y., Saito, S., Watanabe, K., Omiya, N., Murano, M., ... Tajiri, H. (2012). New reduced volume preparation regimen in colon capsule endoscopy. World Journal of Gastroenterology, 18(17), 2092-2098. https://doi.org/10.3748/wjg.v18.i17.2092
Kakugawa, Yasuo ; Saito, Yutaka ; Saito, Shoichi ; Watanabe, Kenji ; Omiya, Naoki ; Murano, Mitsuyuki ; Oka, Shiro ; Arakawa, Tetsuo ; Goto, Hidemi ; Higuchi, Kazuhide ; Tanaka, Shinji ; Ishikawa, Hideki ; Tajiri, Hisao. / New reduced volume preparation regimen in colon capsule endoscopy. In: World Journal of Gastroenterology. 2012 ; Vol. 18, No. 17. pp. 2092-2098.
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author = "Yasuo Kakugawa and Yutaka Saito and Shoichi Saito and Kenji Watanabe and Naoki Omiya and Mitsuyuki Murano and Shiro Oka and Tetsuo Arakawa and Hidemi Goto and Kazuhide Higuchi and Shinji Tanaka and Hideki Ishikawa and Hisao Tajiri",
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Kakugawa, Y, Saito, Y, Saito, S, Watanabe, K, Omiya, N, Murano, M, Oka, S, Arakawa, T, Goto, H, Higuchi, K, Tanaka, S, Ishikawa, H & Tajiri, H 2012, 'New reduced volume preparation regimen in colon capsule endoscopy', World Journal of Gastroenterology, vol. 18, no. 17, pp. 2092-2098. https://doi.org/10.3748/wjg.v18.i17.2092

New reduced volume preparation regimen in colon capsule endoscopy. / Kakugawa, Yasuo; Saito, Yutaka; Saito, Shoichi; Watanabe, Kenji; Omiya, Naoki; Murano, Mitsuyuki; Oka, Shiro; Arakawa, Tetsuo; Goto, Hidemi; Higuchi, Kazuhide; Tanaka, Shinji; Ishikawa, Hideki; Tajiri, Hisao.

In: World Journal of Gastroenterology, Vol. 18, No. 17, 07.05.2012, p. 2092-2098.

Research output: Contribution to journalReview article

TY - JOUR

T1 - New reduced volume preparation regimen in colon capsule endoscopy

AU - Kakugawa, Yasuo

AU - Saito, Yutaka

AU - Saito, Shoichi

AU - Watanabe, Kenji

AU - Omiya, Naoki

AU - Murano, Mitsuyuki

AU - Oka, Shiro

AU - Arakawa, Tetsuo

AU - Goto, Hidemi

AU - Higuchi, Kazuhide

AU - Tanaka, Shinji

AU - Ishikawa, Hideki

AU - Tajiri, Hisao

PY - 2012/5/7

Y1 - 2012/5/7

N2 - AIM: To evaluate the effectiveness of our proposed bowel preparation method for colon capsule endoscopy. METHODS: A pilot, multicenter, randomized controlled trial compared our proposed "reduced volume method" (group A) with the "conventional volume method" (group B) preparation regimens. Group A did not drink polyethylene glycol electrolyte lavage solution (PEGELS) the day before the capsule procedure, while group B drank 2 L. During the procedure day, groups A and B drank 2 L and 1 L of PEG-ELS, respectively, and swallowed the colon capsule (PillCam COLON® capsule). Two hours later the first booster of 100 g magnesium citrate mixed with 900 mL water was administered to both groups, and the second booster was administered six hours post capsule ingestion as long as the capsule had not been excreted by that time. Capsule videos were reviewed for grading of cleansing level. RESULTS: Sixty-four subjects were enrolled, with results from 60 analyzed. Groups A and B included 31 and 29 subjects, respectively. Twenty-nine (94%) subjects in group A and 25 (86%) subjects in group B had adequate bowel preparation (ns). Twenty-two (71%) of the 31 subjects in group A excreted the capsule within its battery life compared to 16 (55%) of the 29 subjects in group B (ns). Of the remaining 22 subjects whose capsules were not excreted within the battery life, all of the capsules reached the left side colon before they stopped functioning. A single adverse event was reported in one subject who had mild symptoms of nausea and vomiting one hour after starting to drink PEG-ELS, due to ingesting the PEG-ELS faster than recommended. CONCLUSION: Our proposed reduced volume bowel preparation method for colon capsule without PEG-ELS during the days before the procedure was as effective as the conventional volume method.

AB - AIM: To evaluate the effectiveness of our proposed bowel preparation method for colon capsule endoscopy. METHODS: A pilot, multicenter, randomized controlled trial compared our proposed "reduced volume method" (group A) with the "conventional volume method" (group B) preparation regimens. Group A did not drink polyethylene glycol electrolyte lavage solution (PEGELS) the day before the capsule procedure, while group B drank 2 L. During the procedure day, groups A and B drank 2 L and 1 L of PEG-ELS, respectively, and swallowed the colon capsule (PillCam COLON® capsule). Two hours later the first booster of 100 g magnesium citrate mixed with 900 mL water was administered to both groups, and the second booster was administered six hours post capsule ingestion as long as the capsule had not been excreted by that time. Capsule videos were reviewed for grading of cleansing level. RESULTS: Sixty-four subjects were enrolled, with results from 60 analyzed. Groups A and B included 31 and 29 subjects, respectively. Twenty-nine (94%) subjects in group A and 25 (86%) subjects in group B had adequate bowel preparation (ns). Twenty-two (71%) of the 31 subjects in group A excreted the capsule within its battery life compared to 16 (55%) of the 29 subjects in group B (ns). Of the remaining 22 subjects whose capsules were not excreted within the battery life, all of the capsules reached the left side colon before they stopped functioning. A single adverse event was reported in one subject who had mild symptoms of nausea and vomiting one hour after starting to drink PEG-ELS, due to ingesting the PEG-ELS faster than recommended. CONCLUSION: Our proposed reduced volume bowel preparation method for colon capsule without PEG-ELS during the days before the procedure was as effective as the conventional volume method.

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U2 - 10.3748/wjg.v18.i17.2092

DO - 10.3748/wjg.v18.i17.2092

M3 - Review article

VL - 18

SP - 2092

EP - 2098

JO - World Journal of Gastroenterology

JF - World Journal of Gastroenterology

SN - 1007-9327

IS - 17

ER -