Nitric oxide inhalation is useful in the management of right ventricular failure caused by myocardial infarction

Yoshihito Fujita, Osamu Nishida, Kazuya Sobue, Hiroaki Ito, Nobuyoshi Kusama, Masaaki Inagaki, Hirotada Katsuya

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Objective: To describe hemodynamic improvement in a patient treated with nitric oxide (NO) inhalation in the management of right ventricular failure caused by myocardial infarction. Design: Case report. Setting: An intensive care unit of a university hospital. Patient: A 66-yr-old man with severe right ventricular failure caused by acute myocardial infarction. Interventions: Nitric oxide inhalation through a ventilator circuit. Measurements and Main Results: The patient complained of chest pain. When myocardial infarction was diagnosed, he underwent percutaneous transluminal coronary angioplasty and percutaneous transluminal coronary recanalization, but they were not effective. We instituted intra-aortic balloon pumping and brought the patient to the intensive care unit (ICU). Even with high-dose inotropic support, his hemodynamics deteriorated gradually. On the patient's seventh day in the ICU, we started NO inhalation at 5-10 ppm in an attempt to relieve his right heart failure. Immediately after NO inhalation was started, his hemodynamics improved significantly, and we could wean the patient from intra-aortic balloon pumping. NO inhalation was continued for 9 days and was successfully discontinued without circulatory deterioration. He was discharged from our hospital uneventfully. Conclusion: Nitric oxide inhalation improved hemodynamics in our patient with right ventricular failure after myocardial infarction. Our report suggests that a clinical trial of NO treatment for severe right ventricular failure caused by myocardial infarction is warranted.

Original languageEnglish
Pages (from-to)1379-1381
Number of pages3
JournalCritical Care Medicine
Volume30
Issue number6
DOIs
Publication statusPublished - 01-01-2002
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Critical Care and Intensive Care Medicine

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