No association with the neuregulin 1 haplotype to Japanese schizophrenia

N. Iwata, T. Suzuki, M. Ikeda, T. Kitajima, Y. Yamanouchi, T. Inada, N. Ozaki

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86 Citations (Scopus)


Previous studies show that genetic haplotype within the neuregulin 1 gene (NRG1) increase the risk of developing schizophrenia. The authors described a negative replication that a haplotype of NRG1 did not associate with schizophrenia. Of 607 Japanese schizophrenic patients and 515 controls, the estimated frequency of the core at-risk haplotype had no difference between patients (4.5%) and controls (4.3%). The data suggests that NRG1 haplotype is unlikely to be associated with increased risk of schrizophrenia.

Original languageEnglish
Pages (from-to)126-127+118
JournalMolecular Psychiatry
Issue number2
Publication statusPublished - 2004

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience


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