Optimal prosthetic graft design for small diameter vascular grafts

Toshiya Nishibe, Yuka Kondo, Akihito Muto, Alan Dardik

Research output: Contribution to journalReview articlepeer-review

30 Citations (Scopus)


Autogenous vein and arterial grafts, such as great saphenous veins and internal mammary and radial arteries, remain the gold standard conduits for vascular reconstruction. Expanded polytetrafluoroethylene (PTFE) grafts, which exhibit little inflammatory and thrombogenic reactivity, are the most commonly used material of choice for small diameter vascular grafts when autogenous grafts are not available. Several modifications of the basic graft have been attempted to enhance graft healing of expanded PTFE grafts, and little but definite experimental and clinical improvement has been achieved so far. The technique of vascular tissue engineering, in combination with stem cell research, may hold the key for the creation of a practical and successful small diameter prosthetic graft.

Original languageEnglish
Pages (from-to)356-360
Number of pages5
Issue number6
Publication statusPublished - 11-2007

All Science Journal Classification (ASJC) codes

  • Surgery
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Optimal prosthetic graft design for small diameter vascular grafts'. Together they form a unique fingerprint.

Cite this