Oral mucosa graft urethroplasty for complicated urethral strictures

Akio Horiguchi, Makoto Sumitomo, Taiki Kanbara, Yujiro Tsujita, Takahiko Yoshii, Hidehiko Yoshii, Akinori Satoh, Junichi Asakuma, Keiichi Ito, Masamichi Hayakawa, Tomohiko Asano

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


(Objective) We evaluated the efficacy and outcome of one-stage oral mucosa graft urethroplasty, which is currently the procedure of choice for treating lengthy and complicated urethral strictures not amenable to excision and primary end-to-end anastomosis. (Patients and methods) Seven patients 33 to 74 years old (mean age = 53.7) underwent one-stage oral mucosa graft urethroplasty for a stricture in either the bulbar urethra (four patients), penile urethra (two patients), or pan-anterior urethra (one patient). Three of the strictures were due to trauma, one was due to inflammation, and one was due to a failed hypospadia repair. The other two were iatrogenic. All patients had previously undergone either internal urethrotomy or repeated urethral dilation. Three patients received a tube graft, three received a ventral onlay, and one received a dorsal onlay. A free graft of oral mucosa was harvested from the inside of each patient's left cheek, and if necessary to obtain a sufficient length, the harvest was extended to include mucosa from the lower lip and the right cheek. The graft lengths ranged from 2.5 to 12 cm (mean = 4.6 cm). A urethral catheter was left in place for 3 weeks postoperatively. (Results) While no severe complications at the donor site were observed during follow-up periods ranging from 3 to 55 months (mean = 14 months), two patients who had received a tube graft developed distal anastomotic ring strictures that were managed by internal urethrotomy. The other five required no postoperative urological procedure even though one who had received a ventral onlay developed a penoscrotal fistula (Conclusion) Oral mucosa is an ideal urethral graft and oral mucosa graft urethroplasty is an effective procedure for repairing complicated urethral strictures involving long portions of the urethra

Original languageEnglish
Pages (from-to)547-553
Number of pages7
JournalJapanese Journal of Urology
Issue number3
Publication statusPublished - 03-2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Urology


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