Outbreak of CTX-M-3-type extended-spectrum β-lactamase-producing Enterobacter cloacae in a pediatric ward

Naohiko Moriguchi; Yuka Itahashi; Nobutada Tabata; Toshiaki Yamazumi; Itaru Furuta; Naohiro Shibata; Yoshichika Arakawa; Hiroshi Miyata

doi:10.1007/s10156-007-0526-7

Outbreak of CTX-M-3-type extended-spectrum β-lactamase-producing Enterobacter cloacae in a pediatric ward

Naohiko Moriguchi, Yuka Itahashi, Nobutada Tabata, Toshiaki Yamazumi, Itaru Furuta, Naohiro Shibata, Yoshichika Arakawa, Hiroshi Miyata

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

A first resistant strain of Enterobacter cloacae was isolated from a blood specimen in a pediatric patient with immature teratoma-developed sepsis after combination chemotherapy. The strain produced extended-spectrum β-lactamase (ESBL), and the same ESBL-producing strains were detected in urine samples from other patients in the pediatric ward. All strains harbored genes for bla _CTX-M-3 by polymerase chain reaction (PCR) and sequencing analysis. Analysis of pulsed-field gel electrophoresis revealed that all strains were the same clonal type. These results suggest that ESBL-producing strains might be transmitted in the ward via contact among patients or medical staff.

Original language	English
Pages (from-to)	263-266
Number of pages	4
Journal	Journal of Infection and Chemotherapy
Volume	13
Issue number	4
DOIs	https://doi.org/10.1007/s10156-007-0526-7
Publication status	Published - 08-2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Pharmacology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10156-007-0526-7

Cite this

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title = "Outbreak of CTX-M-3-type extended-spectrum β-lactamase-producing Enterobacter cloacae in a pediatric ward",

abstract = "A first resistant strain of Enterobacter cloacae was isolated from a blood specimen in a pediatric patient with immature teratoma-developed sepsis after combination chemotherapy. The strain produced extended-spectrum β-lactamase (ESBL), and the same ESBL-producing strains were detected in urine samples from other patients in the pediatric ward. All strains harbored genes for bla CTX-M-3 by polymerase chain reaction (PCR) and sequencing analysis. Analysis of pulsed-field gel electrophoresis revealed that all strains were the same clonal type. These results suggest that ESBL-producing strains might be transmitted in the ward via contact among patients or medical staff.",

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AU - Moriguchi, Naohiko

AU - Itahashi, Yuka

AU - Tabata, Nobutada

AU - Yamazumi, Toshiaki

AU - Furuta, Itaru

AU - Shibata, Naohiro

AU - Arakawa, Yoshichika

AU - Miyata, Hiroshi

PY - 2007/8

Y1 - 2007/8

N2 - A first resistant strain of Enterobacter cloacae was isolated from a blood specimen in a pediatric patient with immature teratoma-developed sepsis after combination chemotherapy. The strain produced extended-spectrum β-lactamase (ESBL), and the same ESBL-producing strains were detected in urine samples from other patients in the pediatric ward. All strains harbored genes for bla CTX-M-3 by polymerase chain reaction (PCR) and sequencing analysis. Analysis of pulsed-field gel electrophoresis revealed that all strains were the same clonal type. These results suggest that ESBL-producing strains might be transmitted in the ward via contact among patients or medical staff.

AB - A first resistant strain of Enterobacter cloacae was isolated from a blood specimen in a pediatric patient with immature teratoma-developed sepsis after combination chemotherapy. The strain produced extended-spectrum β-lactamase (ESBL), and the same ESBL-producing strains were detected in urine samples from other patients in the pediatric ward. All strains harbored genes for bla CTX-M-3 by polymerase chain reaction (PCR) and sequencing analysis. Analysis of pulsed-field gel electrophoresis revealed that all strains were the same clonal type. These results suggest that ESBL-producing strains might be transmitted in the ward via contact among patients or medical staff.

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Outbreak of CTX-M-3-type extended-spectrum β-lactamase-producing Enterobacter cloacae in a pediatric ward

Abstract

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