TY - JOUR
T1 - Outcomes after drug-coated balloon treatment for patients with calcified coronary lesions
AU - Ito, Ryuta
AU - Ueno, Katsumi
AU - Yoshida, Tamami
AU - Takahashi, Hiroshi
AU - Tatsumi, Tomohiko
AU - Hashimoto, Yasumasa
AU - Kojima, Yoshinobu
AU - Kitamura, Tomoya
AU - Morita, Norihiko
N1 - Publisher Copyright:
© 2017 Wiley Periodicals, Inc.
PY - 2018/8
Y1 - 2018/8
N2 - Objectives: To investigate the efficacy of drug-coated balloon (DCB) for calcified coronary lesions. Background: Calcified coronary lesions is associated with poor clinical outcomes after revascularization. Recently, DCB is emerging as an alternative strategy for de novo coronary lesions. However, reports describing the efficacy of DCB for calcified coronary lesions are limited. Methods: A total of 81 patients (96 lesions) who electively underwent DCB treatment for de novo coronary lesions were enrolled: 46 patients (55 lesions) in the calcified group and 35 patients (41 lesions) in the non-calcified group. Angiographic follow-up data and clinical outcomes after the procedure were evaluated. Results: The diameter of the DCB used was 2.5 ± 0.5 mm. No bail-out stenting was observed after DCB treatment. Rotational atherectomy was used in 82% of lesions in the calcified group. Follow-up angiography (median, 6.5 months after intervention) was performed for 59 patients (30 in the calcified group and 29 in the non-calcified group). Late lumen loss and rates of restenosis were comparable between the groups (0.03 mm in the calcified group vs −0.18 mm in the non-calcified group, P = 0.093 and 13.9% vs 3.03%, P = 0.095, respectively). The survival rates for target lesion revascularization free survival and major adverse cardiac events at 2 years were comparable between the groups (85.3% vs 93.4%, P = 0.64 and 81.4% vs 88.5%, P = 0.57, respectively). Conclusion: Calcified coronary lesions might dilute the effect of DCB. However, clinical outcomes in the calcified group were similar to those in the non-calcified group.
AB - Objectives: To investigate the efficacy of drug-coated balloon (DCB) for calcified coronary lesions. Background: Calcified coronary lesions is associated with poor clinical outcomes after revascularization. Recently, DCB is emerging as an alternative strategy for de novo coronary lesions. However, reports describing the efficacy of DCB for calcified coronary lesions are limited. Methods: A total of 81 patients (96 lesions) who electively underwent DCB treatment for de novo coronary lesions were enrolled: 46 patients (55 lesions) in the calcified group and 35 patients (41 lesions) in the non-calcified group. Angiographic follow-up data and clinical outcomes after the procedure were evaluated. Results: The diameter of the DCB used was 2.5 ± 0.5 mm. No bail-out stenting was observed after DCB treatment. Rotational atherectomy was used in 82% of lesions in the calcified group. Follow-up angiography (median, 6.5 months after intervention) was performed for 59 patients (30 in the calcified group and 29 in the non-calcified group). Late lumen loss and rates of restenosis were comparable between the groups (0.03 mm in the calcified group vs −0.18 mm in the non-calcified group, P = 0.093 and 13.9% vs 3.03%, P = 0.095, respectively). The survival rates for target lesion revascularization free survival and major adverse cardiac events at 2 years were comparable between the groups (85.3% vs 93.4%, P = 0.64 and 81.4% vs 88.5%, P = 0.57, respectively). Conclusion: Calcified coronary lesions might dilute the effect of DCB. However, clinical outcomes in the calcified group were similar to those in the non-calcified group.
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U2 - 10.1111/joic.12484
DO - 10.1111/joic.12484
M3 - Article
C2 - 29266411
AN - SCOPUS:85038413902
SN - 0896-4327
VL - 31
SP - 436
EP - 441
JO - Journal of Interventional Cardiology
JF - Journal of Interventional Cardiology
IS - 4
ER -