Outcomes of surgical versus endovascular repair of unruptured brain aneurysms in individuals aged ≥75 years

Joji Inamasu, Teppei Tanaka, Akiyo Sadato, Motoharu Hayakawa, Kazuhide Adachi, Takuro Hayashi, Yoko Kato, Yuichi Hirose

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Aim: Therapeutic intervention to repair unruptured aneurysms (UA) has not been strongly recommended for the elderly, because of their limited life expectancy and low annual bleeding rate. However, physically and mentally healthy older adults with seemingly high risk of aneurysmal bleeding might benefit from having their UA repaired. Methods: A single-center retrospective study was carried out. Among 1078 patients admitted for treatment of UA between 2007 and 2011, the number of patients aged ≥75 years who underwent surgical and endovascular repair of UA was 30 and 31, respectively. The operative and mid-term outcomes were compared between the two groups. For evaluation of the operative outcomes, frequency and types of adverse events that occurred within 30 days of intervention (operative morbidity) were described. For assessment of the mid-term outcomes, activities of daily living (ADL) at 24 months after intervention were evaluated with the modified Rankin Scale (mRS). Results: The operative morbidity rate was 6.7% in the open surgery group and 6.5% in the endovascular surgery group, and they did not differ significantly. The frequency of patients with mRS 0-2 at 24 months after intervention was 85.7% in the open surgery group and 82.8% in the endovascular surgery group, and they did not differ significantly. The adverse event rate of patients with middle cerebral artery aneurysms treated endovascularly was high (80%). Conclusions: The outcomes of individuals aged ≥75 years who underwent repair of UA were generally favorable in either treatment group, with more than 80% living an independent life at 24 months after intervention.

Original languageEnglish
Pages (from-to)858-863
Number of pages6
JournalGeriatrics and Gerontology International
Volume14
Issue number4
DOIs
Publication statusPublished - 01-10-2014

All Science Journal Classification (ASJC) codes

  • Health(social science)
  • Gerontology
  • Geriatrics and Gerontology

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