Abstract
We investigated ertapenem-susceptible and -resistant extended-spectrum β-lactamase-producing Enterobacter cloacae isolates obtained from the same patient. Gene transcription of OmpD and OmpF was diminished in the ertapenem-resistant isolate. An efflux pump inhibitor decreased the MICs of ertapenem in the resistant strain, suggesting a potential role of efflux pumps in ertapenem resistance.
Original language | English |
---|---|
Pages (from-to) | 2833-2835 |
Number of pages | 3 |
Journal | Antimicrobial agents and chemotherapy |
Volume | 50 |
Issue number | 8 |
DOIs | |
Publication status | Published - 08-2006 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases