Overexpression of dominant-negative mutant hepatocyte nuclear factor-1α in pancreatic β-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced β-cell proliferation, and diabetes

Kazuya Yamagata, Takao Nammo, Makoto Moriwaki, Arisa Ihara, Katsumi Iizuka, Qin Yang, Tomomi Satoh, Ming Li, Rikako Uenaka, Kohei Okita, Hiromi Iwahashi, Qian Zhu, Yang Cao, Akihisa Imagawa, Yoshihiro Tochino, Toshiaki Hanafusa, Jun Ichiro Miyagawa, Yuji Matsuzawa

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Medicine & Life Sciences