Overview of the BioBank Japan Project: Study design and profile

BioBank Japan Cooperative Hospital Group

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

Background: The BioBank Japan (BBJ) Project was launched in 2003 with the aim of providing evidence for the implementation of personalized medicine by constructing a large, patient-based biobank (BBJ). This report describes the study design and profile of BBJ participants who were registered during the first 5-year period of the project. Methods: The BBJ is a registry of patients diagnosed with any of 47 target common diseases. Patients were enrolled at 12 cooperative medical institutes all over Japan from June 2003 to March 2008. Clinical information was collected annually via interviews and medical record reviews until 2013. We collected DNA from all participants at baseline and collected annual serum samples until 2013. In addition, we followed patients who reported a history of 32 of the 47 target diseases to collect survival data, including cause of death. Results: During the 5-year period, 200,000 participants were registered in the study. The total number of cases was 291,274 at baseline. Baseline data for 199,982 participants (53.1% male) were available for analysis. The average age at entry was 62.7 years for men and 61.5 years for women. Follow-up surveys were performed for participants with any of 32 diseases, and survival time data for 141,612 participants were available for analysis.

Original languageEnglish
Pages (from-to)S2-S8
JournalJournal of epidemiology
Volume27
Issue number3
DOIs
Publication statusPublished - 01-01-2017

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Japan
Precision Medicine
Survival
Medical Records
Registries
Cause of Death
Interviews
DNA
Serum

All Science Journal Classification (ASJC) codes

  • Epidemiology

Cite this

BioBank Japan Cooperative Hospital Group. / Overview of the BioBank Japan Project : Study design and profile. In: Journal of epidemiology. 2017 ; Vol. 27, No. 3. pp. S2-S8.
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Overview of the BioBank Japan Project : Study design and profile. / BioBank Japan Cooperative Hospital Group.

In: Journal of epidemiology, Vol. 27, No. 3, 01.01.2017, p. S2-S8.

Research output: Contribution to journalArticle

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AU - BioBank Japan Cooperative Hospital Group

AU - Nagai, Akiko

AU - Hirata, Makoto

AU - Kamatani, Yoichiro

AU - Muto, Kaori

AU - Matsuda, Koichi

AU - Kiyohara, Yutaka

AU - Ninomiya, Toshiharu

AU - Tamakoshi, Akiko

AU - Yamagata, Zentaro

AU - Mushiroda, Taisei

AU - Murakami, Yoshinori

AU - Yuji, Koichiro

AU - Furukawa, Yoichi

AU - Zembutsu, Hitoshi

AU - Tanaka, Toshihiro

AU - Ohnishi, Yozo

AU - Nakamura, Yusuke

AU - Kubo, Michiaki

AU - Shiono, Masaki

AU - Misumi, Kazuo

AU - Kaieda, Reiji

AU - Harada, Hiromasa

AU - Minami, Shiro

AU - Kubo, Michiaki

AU - Emoto, Naoya

AU - Daida, Hiroyuki

AU - Miyauchi, Katsumi

AU - Murakami, Akira

AU - Asai, Satoshi

AU - Moriyama, Mitsuhiko

AU - Takahashi, Yasuo

AU - Fujioka, Tomoaki

AU - Obara, Wataru

AU - Mori, Seijiro

AU - Ito, Hideki

AU - Nagayama, Satoshi

AU - Miki, Yoshio

AU - Masumoto, Akihide

AU - Yamada, Akira

AU - Nishizawa, Yasuko

AU - Kodama, Ken

AU - Kutsumi, Hiromu

AU - Sugimoto, Yoshihisa

AU - Koretsune, Yukihiro

AU - Kusuoka, Hideo

AU - Yanai, Hideki

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