TY - JOUR
T1 - Oxygen-enhanced MR imaging
T2 - Correlation with postsurgical lung function in patients with lung cancer
AU - Ohno, Yoshiharu
AU - Hatabu, Hiroto
AU - Higashino, Takanori
AU - Nogami, Munenobu
AU - Takenaka, Daisuke
AU - Watanabe, Hirokazu
AU - Van Cauteren, Marc
AU - Yoshimura, Masahiro
AU - Satouchi, Miyako
AU - Nishimura, Yoshihiro
AU - Sugimura, Kazuro
PY - 2005/8
Y1 - 2005/8
N2 - PURPOSE: To prospectively determine if lung function as assessed with oxygen-enhanced magnetic resonance (MR) imaging correlates with postsurgical lung function in patients with lung cancer, as compared with quantitative and qualitative findings of computed tomography (CT) and scintigraphy. MATERIALS AND METHODS: Study received institutional review board approval, and informed patient consent was obtained. Thirty consecutive patients (16 men and 14 women, aged 44-81 years; mean age, 65 years) considered candidates for lung resection underwent oxygen-enhanced MR imaging, CT, perfusion scintigraphy, and measurement of forced expiratory volume in 1 second (FEV1). A respiratory-synchronized inversion-recovery half-Fourier single-shot turbo spin-echo MR sequence was used for data acquisition. Correlation of postsurgical lung function (postsurgical FEV1) as determined with oxygen-enhanced MR imaging (FEV1MR), quantitative assessment with CT (FEV 1Quant), qualitative assessment with CT (FEV1Qual), and perfusion scintigraphy (FEV1PS) was conducted with actual postsurgical FEV1, and the limits of agreement of each were determined with Bland-Altman analysis. RESULTS: Correlation between postsurgical FEV1MR and actual postsurgical FEV1 values was excellent (r2 = 0.81, P < .001); it was better than that of FEV 1Qual (r2 = 0.76) and FEV1PS (r2 = 0.77) and similar to that of FEV1Quant (r2 = 0.81) values. The limits of agreement of FEV1MR were between -9.9% and 10.9%. CONCLUSION: Oxygen-enhanced MR imaging can be used to predict posturgical lung function in patients with lung cancer, similar to quantitative CT.
AB - PURPOSE: To prospectively determine if lung function as assessed with oxygen-enhanced magnetic resonance (MR) imaging correlates with postsurgical lung function in patients with lung cancer, as compared with quantitative and qualitative findings of computed tomography (CT) and scintigraphy. MATERIALS AND METHODS: Study received institutional review board approval, and informed patient consent was obtained. Thirty consecutive patients (16 men and 14 women, aged 44-81 years; mean age, 65 years) considered candidates for lung resection underwent oxygen-enhanced MR imaging, CT, perfusion scintigraphy, and measurement of forced expiratory volume in 1 second (FEV1). A respiratory-synchronized inversion-recovery half-Fourier single-shot turbo spin-echo MR sequence was used for data acquisition. Correlation of postsurgical lung function (postsurgical FEV1) as determined with oxygen-enhanced MR imaging (FEV1MR), quantitative assessment with CT (FEV 1Quant), qualitative assessment with CT (FEV1Qual), and perfusion scintigraphy (FEV1PS) was conducted with actual postsurgical FEV1, and the limits of agreement of each were determined with Bland-Altman analysis. RESULTS: Correlation between postsurgical FEV1MR and actual postsurgical FEV1 values was excellent (r2 = 0.81, P < .001); it was better than that of FEV 1Qual (r2 = 0.76) and FEV1PS (r2 = 0.77) and similar to that of FEV1Quant (r2 = 0.81) values. The limits of agreement of FEV1MR were between -9.9% and 10.9%. CONCLUSION: Oxygen-enhanced MR imaging can be used to predict posturgical lung function in patients with lung cancer, similar to quantitative CT.
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U2 - 10.1148/radiol.2361040005
DO - 10.1148/radiol.2361040005
M3 - Article
C2 - 15972343
AN - SCOPUS:22544453578
SN - 0033-8419
VL - 236
SP - 704
EP - 711
JO - Radiology
JF - Radiology
IS - 2
ER -
