Pain relief of oral ulcer by dibucaine-film

Keiko Yamamura; Toshihisa Yotsuyanagi; Tomomitsu Okamoto; Toshitaka Nabeshima

doi:10.1016/S0304-3959(99)00164-5

Pain relief of oral ulcer by dibucaine-film

Keiko Yamamura, Toshihisa Yotsuyanagi, Tomomitsu Okamoto, Toshitaka Nabeshima

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

A water-soluble three-layered oral mucosa-adhesive film made from hydroxypropyl cellulose containing dibucaine (0.25 mg of drug/cm²) was designed for alleviation of severe pain due to oral ulcers, caused by chemotherapy and/or radiotherapy. We report two patients with constant severe pain ulcers treated with the dibucaine film. Patients were asked to record the time that pain was relieved while chewing following first application of the film. Pain relief lasted for 2-5 h after application of the dibucaine film.

Original language	English
Pages (from-to)	625-626
Number of pages	2
Journal	Pain
Volume	83
Issue number	3
DOIs	https://doi.org/10.1016/S0304-3959(99)00164-5
Publication status	Published - 01-12-1999
Externally published	Yes

All Science Journal Classification (ASJC) codes

Neurology
Clinical Neurology
Anesthesiology and Pain Medicine

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10.1016/S0304-3959(99)00164-5

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AU - Okamoto, Tomomitsu

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AB - A water-soluble three-layered oral mucosa-adhesive film made from hydroxypropyl cellulose containing dibucaine (0.25 mg of drug/cm2) was designed for alleviation of severe pain due to oral ulcers, caused by chemotherapy and/or radiotherapy. We report two patients with constant severe pain ulcers treated with the dibucaine film. Patients were asked to record the time that pain was relieved while chewing following first application of the film. Pain relief lasted for 2-5 h after application of the dibucaine film.

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Pain relief of oral ulcer by dibucaine-film

Abstract

All Science Journal Classification (ASJC) codes

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