TY - JOUR
T1 - Pancreatic endocrine neoplasm can mimic serous cystadenoma
AU - Imaoka, Hiroshi
AU - Yamao, Kenji
AU - Salem, Ahmed A.S.
AU - Sawaki, Akira
AU - Takahashi, Kuniyuki
AU - Mizuno, Nobumasa
AU - Kawai, Hiroki
AU - Tajika, Masahiro
AU - Isaka, Toshifumi
AU - Okamoto, Yasuyuki
AU - Shimizu, Yasuhiro
AU - Yanagisawa, Akio
PY - 2005/6
Y1 - 2005/6
N2 - A 57-yr-old female patient was referred to our hospital with a cystic lesion of the head of the pancreas that had been noted on abdominal computed tomography (CT). Endoscopic ultrasonography (EUS) showed a 3.0 cm rounded mass in the head of the pancreas. EUS images showed that the tumor had a solid component consisting of multiple microcysts separated by septae and a cystic component consisting of a macrocystic lesion. Thus, the tumor was suspected of being a serous cystadenoma (SCA). However, the histopathological diagnosis based on endoscopic ultrasound- guided fine-needle-aspiration biopsy (EUS-FNAB) was that of a pancreatic endocrine neoplasm (PEN). Surgical resection was performed. Despite having very similar macroscopic findings to SCA, microscopic examination revealed that the patient's tumor was definitely a PEN. This case suggests that it is very difficult to distinguish PENs from SCAs based solely on imaging methods. EUS-FNAB is essential for determining the appropriate therapeutic strategy, as it provides the histopathological diagnosis.
AB - A 57-yr-old female patient was referred to our hospital with a cystic lesion of the head of the pancreas that had been noted on abdominal computed tomography (CT). Endoscopic ultrasonography (EUS) showed a 3.0 cm rounded mass in the head of the pancreas. EUS images showed that the tumor had a solid component consisting of multiple microcysts separated by septae and a cystic component consisting of a macrocystic lesion. Thus, the tumor was suspected of being a serous cystadenoma (SCA). However, the histopathological diagnosis based on endoscopic ultrasound- guided fine-needle-aspiration biopsy (EUS-FNAB) was that of a pancreatic endocrine neoplasm (PEN). Surgical resection was performed. Despite having very similar macroscopic findings to SCA, microscopic examination revealed that the patient's tumor was definitely a PEN. This case suggests that it is very difficult to distinguish PENs from SCAs based solely on imaging methods. EUS-FNAB is essential for determining the appropriate therapeutic strategy, as it provides the histopathological diagnosis.
UR - http://www.scopus.com/inward/record.url?scp=23844439609&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=23844439609&partnerID=8YFLogxK
U2 - 10.1385/ijgc:35:3:217
DO - 10.1385/ijgc:35:3:217
M3 - Article
C2 - 16110124
AN - SCOPUS:23844439609
SN - 0169-4197
VL - 35
SP - 217
EP - 220
JO - International Journal of Gastrointestinal Cancer
JF - International Journal of Gastrointestinal Cancer
IS - 3
ER -