Papillary Clusters as a Diagnostic Pitfall in Urinary Cytology of Pseudosarcomatous Fibromyxoid Tumor of the Bladder: A Case Report

Tadao K. Kobayashi, Masami Ueda, Toshihiro Nishino, Mitsue Muramatsu, Suzuko Moritani, Hideo Seki, Hirotaka Araki, Chiyuki Kaneko

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

BACKGROUND: Pseudosarcomatous fibromyxoid tumor (PFT) of the urinary bladder is an uncommon benign lesion that can involve any site in the bladder. Cellular features of PFT of the bladder are exceedingly rare. We describe the urinary cytology in a PFT patient who displayed numerous papillary fragments that suggested a malignant tumor. CASE: A 52-year-old man was seen at the hospital for evaluation of gross hematuria. At cystoscopy, the urologist observed a 3-cm, smooth, polypoid and ulcerated mass extending from the trigone to the bladder neck. Urinary cytology showed many papillary clusters with irregular nuclear margins in the bloody cell background. No spindle cells were noted. Cytology was interpreted as papillary growth, favor transitional cell carcinoma, grade 2-3. A laparotomy with partial resection of the urinary bladder was carried out, and histologically the tumor was composed of spindle, stellate, fibroblastic cells embedded in myxoid stroma with little collagen. Immunohistochemical and ultrastructural studies revealed the fibroblastic nature of the lesion. The final diagnosis was PFT of the bladder on the basis of histologic examination of the resected material. CONCLUSION: Papillary fragments are a diagnostic pitfall in urinary cytology of PFT lesions.

Original languageEnglish
Pages (from-to)1069-1073
Number of pages5
JournalActa Cytologica
Volume47
Issue number6
DOIs
Publication statusPublished - 01-01-2003

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

Fingerprint Dive into the research topics of 'Papillary Clusters as a Diagnostic Pitfall in Urinary Cytology of Pseudosarcomatous Fibromyxoid Tumor of the Bladder: A Case Report'. Together they form a unique fingerprint.

  • Cite this