Paradoxical infarct in tuberculous meningitis: A case report

Hiroshi Morioka; Shuuichi Matsumoto; Eiji Kojima; Kazuto Takada; Susumu Iwata; Shoutaro Okachi

doi:10.2169/internalmedicine.51.6830

Paradoxical infarct in tuberculous meningitis: A case report

Hiroshi Morioka
, Shuuichi Matsumoto
, Eiji Kojima
, Kazuto Takada
, Susumu Iwata
, Shoutaro Okachi

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

We describe a case of 78-year-old woman with a 1-week history of fever and left hemiparesis. Head magnetic resonance imaging showed a small infarct. After admission, she showed altered consciousness and another small infarct. She finally had diagnoses of miliary tuberculosis (miliary-TB) and tuberculous meningitis (TBM). She recovered after receiving anti-tuberculous therapy (ATT) with prednisolone. However, 5 weeks later, we found another infarct. This is a rare case of TBM with recurrent infarcts in atypical lesions in spite of ATT. We suggest the possibility that the new infarct after ATT was due to a paradoxical reaction.

Original language	English
Pages (from-to)	949-951
Number of pages	3
Journal	Internal Medicine
Volume	51
Issue number	8
DOIs	https://doi.org/10.2169/internalmedicine.51.6830
Publication status	Published - 2012
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Internal Medicine

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10.2169/internalmedicine.51.6830

Cite this

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title = "Paradoxical infarct in tuberculous meningitis: A case report",

abstract = "We describe a case of 78-year-old woman with a 1-week history of fever and left hemiparesis. Head magnetic resonance imaging showed a small infarct. After admission, she showed altered consciousness and another small infarct. She finally had diagnoses of miliary tuberculosis (miliary-TB) and tuberculous meningitis (TBM). She recovered after receiving anti-tuberculous therapy (ATT) with prednisolone. However, 5 weeks later, we found another infarct. This is a rare case of TBM with recurrent infarcts in atypical lesions in spite of ATT. We suggest the possibility that the new infarct after ATT was due to a paradoxical reaction.",

keywords = "Central nervous system tuberculosis, Infarct, Miliary tuberculosis, Paradoxical reaction, Tuberculous meningitis",

author = "Hiroshi Morioka and Shuuichi Matsumoto and Eiji Kojima and Kazuto Takada and Susumu Iwata and Shoutaro Okachi",

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TY - JOUR

T1 - Paradoxical infarct in tuberculous meningitis

T2 - A case report

AU - Morioka, Hiroshi

AU - Matsumoto, Shuuichi

AU - Kojima, Eiji

AU - Takada, Kazuto

AU - Iwata, Susumu

AU - Okachi, Shoutaro

PY - 2012

Y1 - 2012

N2 - We describe a case of 78-year-old woman with a 1-week history of fever and left hemiparesis. Head magnetic resonance imaging showed a small infarct. After admission, she showed altered consciousness and another small infarct. She finally had diagnoses of miliary tuberculosis (miliary-TB) and tuberculous meningitis (TBM). She recovered after receiving anti-tuberculous therapy (ATT) with prednisolone. However, 5 weeks later, we found another infarct. This is a rare case of TBM with recurrent infarcts in atypical lesions in spite of ATT. We suggest the possibility that the new infarct after ATT was due to a paradoxical reaction.

AB - We describe a case of 78-year-old woman with a 1-week history of fever and left hemiparesis. Head magnetic resonance imaging showed a small infarct. After admission, she showed altered consciousness and another small infarct. She finally had diagnoses of miliary tuberculosis (miliary-TB) and tuberculous meningitis (TBM). She recovered after receiving anti-tuberculous therapy (ATT) with prednisolone. However, 5 weeks later, we found another infarct. This is a rare case of TBM with recurrent infarcts in atypical lesions in spite of ATT. We suggest the possibility that the new infarct after ATT was due to a paradoxical reaction.

KW - Central nervous system tuberculosis

KW - Infarct

KW - Miliary tuberculosis

KW - Paradoxical reaction

KW - Tuberculous meningitis

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DO - 10.2169/internalmedicine.51.6830

M3 - Article

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AN - SCOPUS:84859841699

SN - 0918-2918

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EP - 951

JO - Internal Medicine

JF - Internal Medicine

IS - 8

ER -

Paradoxical infarct in tuberculous meningitis: A case report

Abstract

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