Parental history and lifestyle behaviors in relation to mortality from stroke among japanese men and women: The japan collaborative cohort study

Eri Eguchi, Hiroyasu Iso Prof., Yasuhiko Wada, Shogo Kikuchi, Yoshiyuki Watanabe, Akiko Tamakoshi, Mitsuru Mori, Fumio Sakauchi, Yutaka Motohashi, Ichiro Tsuji, Yosikazu Nakamura, Haruo Mikami, Michiko Kurosawa, Naohito Tanabe, Koji Tamakoshi, Kenji Wakai, Shinkan Tokudome, Koji Suzuki, Shuji Hashimoto, Takashi KawamuraKotaro Ozasa, Tsuneharu Miki, Chigusa Date, Kiyomi Sakata, Yoichi Kurozawa, Takesumi Yoshimura, Yoshihisa Fujino, Naoyuki Okamoto, Hideo Shio, Akio Yamamoto, Masahiko Ando, Yoshiharu Hoshiyama, Akira Shibata

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: We assessed the impact of parental history of stroke on stroke mortality, as well as the effect modification between lifestyle and stroke mortality, among Japanese.Methods: In this community-based, prospective cohort study, 22 763 men and 30 928 women aged 40 to 79 years with no history of cardiovascular disease or cancer at baseline (1988-1990) were followed through 2008. We examined the association between parental history of stroke and stroke mortality and estimated the impact of the combination of lifestyle and parental history on stroke mortality in offspring.Results: During a mean follow-up period of 15.9 years, there were 1502 stroke deaths. In both sexes, participants with a parental history of stroke had a higher risk of stroke mortality as compared with those without such a history. The respective multivariable hazard ratio (95% CI) and population attributable fraction were 1.28 (1.10-1.49) and 5.4% in men, 1.22 (1.04-1.43) and 4.3% in women, and 1.25 (1.12-1.40) and 4.8% in all participants, for offspring with a maternal and/or paternal history of stroke. There was an inverse association between healthy-lifestyle score and stroke mortality, irrespective of parental history of stroke. The overall multivariable hazard ratio for the highest (6-8) versus the lowest (0-3) score categories was 0.56 (95% CI, 0.43-0.72) for participants with a maternal and/or paternal history of stroke and 0.44 (0.36-0.53) for those without such a history.Conclusions: Parental history of stroke was associated with stroke mortality in offspring. The inverse association between healthy lifestyle behaviors and stroke mortality, regardless of parental history, suggests that lifestyle modification is beneficial, even among individuals with a parental history of stroke.

Original languageEnglish
Pages (from-to)331-339
Number of pages9
JournalJournal of epidemiology
Volume22
Issue number4
DOIs
Publication statusPublished - 11-10-2012

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Life Style
Japan
Cohort Studies
Stroke
Mortality
History
Mothers
Cardiovascular Diseases

All Science Journal Classification (ASJC) codes

  • Epidemiology

Cite this

Eguchi, Eri ; Iso Prof., Hiroyasu ; Wada, Yasuhiko ; Kikuchi, Shogo ; Watanabe, Yoshiyuki ; Tamakoshi, Akiko ; Mori, Mitsuru ; Sakauchi, Fumio ; Motohashi, Yutaka ; Tsuji, Ichiro ; Nakamura, Yosikazu ; Mikami, Haruo ; Kurosawa, Michiko ; Tanabe, Naohito ; Tamakoshi, Koji ; Wakai, Kenji ; Tokudome, Shinkan ; Suzuki, Koji ; Hashimoto, Shuji ; Kawamura, Takashi ; Ozasa, Kotaro ; Miki, Tsuneharu ; Date, Chigusa ; Sakata, Kiyomi ; Kurozawa, Yoichi ; Yoshimura, Takesumi ; Fujino, Yoshihisa ; Okamoto, Naoyuki ; Shio, Hideo ; Yamamoto, Akio ; Ando, Masahiko ; Hoshiyama, Yoshiharu ; Shibata, Akira. / Parental history and lifestyle behaviors in relation to mortality from stroke among japanese men and women : The japan collaborative cohort study. In: Journal of epidemiology. 2012 ; Vol. 22, No. 4. pp. 331-339.
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abstract = "Background: We assessed the impact of parental history of stroke on stroke mortality, as well as the effect modification between lifestyle and stroke mortality, among Japanese.Methods: In this community-based, prospective cohort study, 22 763 men and 30 928 women aged 40 to 79 years with no history of cardiovascular disease or cancer at baseline (1988-1990) were followed through 2008. We examined the association between parental history of stroke and stroke mortality and estimated the impact of the combination of lifestyle and parental history on stroke mortality in offspring.Results: During a mean follow-up period of 15.9 years, there were 1502 stroke deaths. In both sexes, participants with a parental history of stroke had a higher risk of stroke mortality as compared with those without such a history. The respective multivariable hazard ratio (95{\%} CI) and population attributable fraction were 1.28 (1.10-1.49) and 5.4{\%} in men, 1.22 (1.04-1.43) and 4.3{\%} in women, and 1.25 (1.12-1.40) and 4.8{\%} in all participants, for offspring with a maternal and/or paternal history of stroke. There was an inverse association between healthy-lifestyle score and stroke mortality, irrespective of parental history of stroke. The overall multivariable hazard ratio for the highest (6-8) versus the lowest (0-3) score categories was 0.56 (95{\%} CI, 0.43-0.72) for participants with a maternal and/or paternal history of stroke and 0.44 (0.36-0.53) for those without such a history.Conclusions: Parental history of stroke was associated with stroke mortality in offspring. The inverse association between healthy lifestyle behaviors and stroke mortality, regardless of parental history, suggests that lifestyle modification is beneficial, even among individuals with a parental history of stroke.",
author = "Eri Eguchi and {Iso Prof.}, Hiroyasu and Yasuhiko Wada and Shogo Kikuchi and Yoshiyuki Watanabe and Akiko Tamakoshi and Mitsuru Mori and Fumio Sakauchi and Yutaka Motohashi and Ichiro Tsuji and Yosikazu Nakamura and Haruo Mikami and Michiko Kurosawa and Naohito Tanabe and Koji Tamakoshi and Kenji Wakai and Shinkan Tokudome and Koji Suzuki and Shuji Hashimoto and Takashi Kawamura and Kotaro Ozasa and Tsuneharu Miki and Chigusa Date and Kiyomi Sakata and Yoichi Kurozawa and Takesumi Yoshimura and Yoshihisa Fujino and Naoyuki Okamoto and Hideo Shio and Akio Yamamoto and Masahiko Ando and Yoshiharu Hoshiyama and Akira Shibata",
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Eguchi, E, Iso Prof., H, Wada, Y, Kikuchi, S, Watanabe, Y, Tamakoshi, A, Mori, M, Sakauchi, F, Motohashi, Y, Tsuji, I, Nakamura, Y, Mikami, H, Kurosawa, M, Tanabe, N, Tamakoshi, K, Wakai, K, Tokudome, S, Suzuki, K, Hashimoto, S, Kawamura, T, Ozasa, K, Miki, T, Date, C, Sakata, K, Kurozawa, Y, Yoshimura, T, Fujino, Y, Okamoto, N, Shio, H, Yamamoto, A, Ando, M, Hoshiyama, Y & Shibata, A 2012, 'Parental history and lifestyle behaviors in relation to mortality from stroke among japanese men and women: The japan collaborative cohort study', Journal of epidemiology, vol. 22, no. 4, pp. 331-339. https://doi.org/10.2188/jea.JE20110163

Parental history and lifestyle behaviors in relation to mortality from stroke among japanese men and women : The japan collaborative cohort study. / Eguchi, Eri; Iso Prof., Hiroyasu; Wada, Yasuhiko; Kikuchi, Shogo; Watanabe, Yoshiyuki; Tamakoshi, Akiko; Mori, Mitsuru; Sakauchi, Fumio; Motohashi, Yutaka; Tsuji, Ichiro; Nakamura, Yosikazu; Mikami, Haruo; Kurosawa, Michiko; Tanabe, Naohito; Tamakoshi, Koji; Wakai, Kenji; Tokudome, Shinkan; Suzuki, Koji; Hashimoto, Shuji; Kawamura, Takashi; Ozasa, Kotaro; Miki, Tsuneharu; Date, Chigusa; Sakata, Kiyomi; Kurozawa, Yoichi; Yoshimura, Takesumi; Fujino, Yoshihisa; Okamoto, Naoyuki; Shio, Hideo; Yamamoto, Akio; Ando, Masahiko; Hoshiyama, Yoshiharu; Shibata, Akira.

In: Journal of epidemiology, Vol. 22, No. 4, 11.10.2012, p. 331-339.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Parental history and lifestyle behaviors in relation to mortality from stroke among japanese men and women

T2 - The japan collaborative cohort study

AU - Eguchi, Eri

AU - Iso Prof., Hiroyasu

AU - Wada, Yasuhiko

AU - Kikuchi, Shogo

AU - Watanabe, Yoshiyuki

AU - Tamakoshi, Akiko

AU - Mori, Mitsuru

AU - Sakauchi, Fumio

AU - Motohashi, Yutaka

AU - Tsuji, Ichiro

AU - Nakamura, Yosikazu

AU - Mikami, Haruo

AU - Kurosawa, Michiko

AU - Tanabe, Naohito

AU - Tamakoshi, Koji

AU - Wakai, Kenji

AU - Tokudome, Shinkan

AU - Suzuki, Koji

AU - Hashimoto, Shuji

AU - Kawamura, Takashi

AU - Ozasa, Kotaro

AU - Miki, Tsuneharu

AU - Date, Chigusa

AU - Sakata, Kiyomi

AU - Kurozawa, Yoichi

AU - Yoshimura, Takesumi

AU - Fujino, Yoshihisa

AU - Okamoto, Naoyuki

AU - Shio, Hideo

AU - Yamamoto, Akio

AU - Ando, Masahiko

AU - Hoshiyama, Yoshiharu

AU - Shibata, Akira

PY - 2012/10/11

Y1 - 2012/10/11

N2 - Background: We assessed the impact of parental history of stroke on stroke mortality, as well as the effect modification between lifestyle and stroke mortality, among Japanese.Methods: In this community-based, prospective cohort study, 22 763 men and 30 928 women aged 40 to 79 years with no history of cardiovascular disease or cancer at baseline (1988-1990) were followed through 2008. We examined the association between parental history of stroke and stroke mortality and estimated the impact of the combination of lifestyle and parental history on stroke mortality in offspring.Results: During a mean follow-up period of 15.9 years, there were 1502 stroke deaths. In both sexes, participants with a parental history of stroke had a higher risk of stroke mortality as compared with those without such a history. The respective multivariable hazard ratio (95% CI) and population attributable fraction were 1.28 (1.10-1.49) and 5.4% in men, 1.22 (1.04-1.43) and 4.3% in women, and 1.25 (1.12-1.40) and 4.8% in all participants, for offspring with a maternal and/or paternal history of stroke. There was an inverse association between healthy-lifestyle score and stroke mortality, irrespective of parental history of stroke. The overall multivariable hazard ratio for the highest (6-8) versus the lowest (0-3) score categories was 0.56 (95% CI, 0.43-0.72) for participants with a maternal and/or paternal history of stroke and 0.44 (0.36-0.53) for those without such a history.Conclusions: Parental history of stroke was associated with stroke mortality in offspring. The inverse association between healthy lifestyle behaviors and stroke mortality, regardless of parental history, suggests that lifestyle modification is beneficial, even among individuals with a parental history of stroke.

AB - Background: We assessed the impact of parental history of stroke on stroke mortality, as well as the effect modification between lifestyle and stroke mortality, among Japanese.Methods: In this community-based, prospective cohort study, 22 763 men and 30 928 women aged 40 to 79 years with no history of cardiovascular disease or cancer at baseline (1988-1990) were followed through 2008. We examined the association between parental history of stroke and stroke mortality and estimated the impact of the combination of lifestyle and parental history on stroke mortality in offspring.Results: During a mean follow-up period of 15.9 years, there were 1502 stroke deaths. In both sexes, participants with a parental history of stroke had a higher risk of stroke mortality as compared with those without such a history. The respective multivariable hazard ratio (95% CI) and population attributable fraction were 1.28 (1.10-1.49) and 5.4% in men, 1.22 (1.04-1.43) and 4.3% in women, and 1.25 (1.12-1.40) and 4.8% in all participants, for offspring with a maternal and/or paternal history of stroke. There was an inverse association between healthy-lifestyle score and stroke mortality, irrespective of parental history of stroke. The overall multivariable hazard ratio for the highest (6-8) versus the lowest (0-3) score categories was 0.56 (95% CI, 0.43-0.72) for participants with a maternal and/or paternal history of stroke and 0.44 (0.36-0.53) for those without such a history.Conclusions: Parental history of stroke was associated with stroke mortality in offspring. The inverse association between healthy lifestyle behaviors and stroke mortality, regardless of parental history, suggests that lifestyle modification is beneficial, even among individuals with a parental history of stroke.

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DO - 10.2188/jea.JE20110163

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