Participation in health check-ups and mortality using propensity score matched cohort analyses

Atsushi Hozawa, Shinichi Kuriyama, Ikue Watanabe, Masako Kakizaki, Kaori Ohmori-Matsuda, Toshimasa Sone, Masato Nagai, Yumi Sugawara, Akemi Nitta, Qiang Li, Takayoshi Ohkubo, Yoshitaka Murakami, Ichiro Tsuji

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective: All Japanese aged ≥40 years are eligible for free annual health check-ups including blood pressure and cholesterol measurements. It is well known that health check-up screenees are more likely to have healthy lifestyles and better health conditions than non-screenees. Therefore, controlling these factors is required to investigate whether screenees have a lower mortality risk than non-screenees independent of their lifestyles or health conditions. Methods: We followed 48,775 Japanese National Health Insurance beneficiaries aged 40-79 years since 1994 for 11 years. We used Cox proportional hazard models adjusted for possible confounding factors. We also performed propensity for use of the health check-up matched cohort analyses. Results: Compared to non-screenees, multiple-adjusted hazard ratios (95% confidence intervals) for all-cause and cardiovascular disease mortality among screenees were 0.74 (0.62-0.88) and 0.65 (0.44-0.95) for men and 0.69 (0.52-0.91) and 0.61 (0.36-1.04) for women, respectively. These relations were also observed when we used propensity matched cohort analyses. Conclusion: This is the first study to show that mortality rates are lower among screenees than non-screenees in Japanese health check-ups when propensity matched cohort analyses were used for adjusting confounding factors. Further prospective studies, including randomized controlled trials, are required to confirm whether screening lowers mortality.

Original languageEnglish
Pages (from-to)397-402
Number of pages6
JournalPreventive Medicine
Volume51
Issue number5
DOIs
Publication statusPublished - 01-11-2010

Fingerprint

Propensity Score
Cohort Studies
Mortality
Health
National Health Programs
Insurance Benefits
Proportional Hazards Models
Life Style
Cardiovascular Diseases
Randomized Controlled Trials
Cholesterol
Prospective Studies
Confidence Intervals
Blood Pressure

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

Hozawa, Atsushi ; Kuriyama, Shinichi ; Watanabe, Ikue ; Kakizaki, Masako ; Ohmori-Matsuda, Kaori ; Sone, Toshimasa ; Nagai, Masato ; Sugawara, Yumi ; Nitta, Akemi ; Li, Qiang ; Ohkubo, Takayoshi ; Murakami, Yoshitaka ; Tsuji, Ichiro. / Participation in health check-ups and mortality using propensity score matched cohort analyses. In: Preventive Medicine. 2010 ; Vol. 51, No. 5. pp. 397-402.
@article{b445d4a93fda497fb51e972a352dda8d,
title = "Participation in health check-ups and mortality using propensity score matched cohort analyses",
abstract = "Objective: All Japanese aged ≥40 years are eligible for free annual health check-ups including blood pressure and cholesterol measurements. It is well known that health check-up screenees are more likely to have healthy lifestyles and better health conditions than non-screenees. Therefore, controlling these factors is required to investigate whether screenees have a lower mortality risk than non-screenees independent of their lifestyles or health conditions. Methods: We followed 48,775 Japanese National Health Insurance beneficiaries aged 40-79 years since 1994 for 11 years. We used Cox proportional hazard models adjusted for possible confounding factors. We also performed propensity for use of the health check-up matched cohort analyses. Results: Compared to non-screenees, multiple-adjusted hazard ratios (95{\%} confidence intervals) for all-cause and cardiovascular disease mortality among screenees were 0.74 (0.62-0.88) and 0.65 (0.44-0.95) for men and 0.69 (0.52-0.91) and 0.61 (0.36-1.04) for women, respectively. These relations were also observed when we used propensity matched cohort analyses. Conclusion: This is the first study to show that mortality rates are lower among screenees than non-screenees in Japanese health check-ups when propensity matched cohort analyses were used for adjusting confounding factors. Further prospective studies, including randomized controlled trials, are required to confirm whether screening lowers mortality.",
author = "Atsushi Hozawa and Shinichi Kuriyama and Ikue Watanabe and Masako Kakizaki and Kaori Ohmori-Matsuda and Toshimasa Sone and Masato Nagai and Yumi Sugawara and Akemi Nitta and Qiang Li and Takayoshi Ohkubo and Yoshitaka Murakami and Ichiro Tsuji",
year = "2010",
month = "11",
day = "1",
doi = "10.1016/j.ypmed.2010.08.017",
language = "English",
volume = "51",
pages = "397--402",
journal = "Preventive Medicine",
issn = "0091-7435",
publisher = "Academic Press Inc.",
number = "5",

}

Hozawa, A, Kuriyama, S, Watanabe, I, Kakizaki, M, Ohmori-Matsuda, K, Sone, T, Nagai, M, Sugawara, Y, Nitta, A, Li, Q, Ohkubo, T, Murakami, Y & Tsuji, I 2010, 'Participation in health check-ups and mortality using propensity score matched cohort analyses', Preventive Medicine, vol. 51, no. 5, pp. 397-402. https://doi.org/10.1016/j.ypmed.2010.08.017

Participation in health check-ups and mortality using propensity score matched cohort analyses. / Hozawa, Atsushi; Kuriyama, Shinichi; Watanabe, Ikue; Kakizaki, Masako; Ohmori-Matsuda, Kaori; Sone, Toshimasa; Nagai, Masato; Sugawara, Yumi; Nitta, Akemi; Li, Qiang; Ohkubo, Takayoshi; Murakami, Yoshitaka; Tsuji, Ichiro.

In: Preventive Medicine, Vol. 51, No. 5, 01.11.2010, p. 397-402.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Participation in health check-ups and mortality using propensity score matched cohort analyses

AU - Hozawa, Atsushi

AU - Kuriyama, Shinichi

AU - Watanabe, Ikue

AU - Kakizaki, Masako

AU - Ohmori-Matsuda, Kaori

AU - Sone, Toshimasa

AU - Nagai, Masato

AU - Sugawara, Yumi

AU - Nitta, Akemi

AU - Li, Qiang

AU - Ohkubo, Takayoshi

AU - Murakami, Yoshitaka

AU - Tsuji, Ichiro

PY - 2010/11/1

Y1 - 2010/11/1

N2 - Objective: All Japanese aged ≥40 years are eligible for free annual health check-ups including blood pressure and cholesterol measurements. It is well known that health check-up screenees are more likely to have healthy lifestyles and better health conditions than non-screenees. Therefore, controlling these factors is required to investigate whether screenees have a lower mortality risk than non-screenees independent of their lifestyles or health conditions. Methods: We followed 48,775 Japanese National Health Insurance beneficiaries aged 40-79 years since 1994 for 11 years. We used Cox proportional hazard models adjusted for possible confounding factors. We also performed propensity for use of the health check-up matched cohort analyses. Results: Compared to non-screenees, multiple-adjusted hazard ratios (95% confidence intervals) for all-cause and cardiovascular disease mortality among screenees were 0.74 (0.62-0.88) and 0.65 (0.44-0.95) for men and 0.69 (0.52-0.91) and 0.61 (0.36-1.04) for women, respectively. These relations were also observed when we used propensity matched cohort analyses. Conclusion: This is the first study to show that mortality rates are lower among screenees than non-screenees in Japanese health check-ups when propensity matched cohort analyses were used for adjusting confounding factors. Further prospective studies, including randomized controlled trials, are required to confirm whether screening lowers mortality.

AB - Objective: All Japanese aged ≥40 years are eligible for free annual health check-ups including blood pressure and cholesterol measurements. It is well known that health check-up screenees are more likely to have healthy lifestyles and better health conditions than non-screenees. Therefore, controlling these factors is required to investigate whether screenees have a lower mortality risk than non-screenees independent of their lifestyles or health conditions. Methods: We followed 48,775 Japanese National Health Insurance beneficiaries aged 40-79 years since 1994 for 11 years. We used Cox proportional hazard models adjusted for possible confounding factors. We also performed propensity for use of the health check-up matched cohort analyses. Results: Compared to non-screenees, multiple-adjusted hazard ratios (95% confidence intervals) for all-cause and cardiovascular disease mortality among screenees were 0.74 (0.62-0.88) and 0.65 (0.44-0.95) for men and 0.69 (0.52-0.91) and 0.61 (0.36-1.04) for women, respectively. These relations were also observed when we used propensity matched cohort analyses. Conclusion: This is the first study to show that mortality rates are lower among screenees than non-screenees in Japanese health check-ups when propensity matched cohort analyses were used for adjusting confounding factors. Further prospective studies, including randomized controlled trials, are required to confirm whether screening lowers mortality.

UR - http://www.scopus.com/inward/record.url?scp=77958168332&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77958168332&partnerID=8YFLogxK

U2 - 10.1016/j.ypmed.2010.08.017

DO - 10.1016/j.ypmed.2010.08.017

M3 - Article

VL - 51

SP - 397

EP - 402

JO - Preventive Medicine

JF - Preventive Medicine

SN - 0091-7435

IS - 5

ER -