Abstract
Objective: All Japanese aged ≥40 years are eligible for free annual health check-ups including blood pressure and cholesterol measurements. It is well known that health check-up screenees are more likely to have healthy lifestyles and better health conditions than non-screenees. Therefore, controlling these factors is required to investigate whether screenees have a lower mortality risk than non-screenees independent of their lifestyles or health conditions. Methods: We followed 48,775 Japanese National Health Insurance beneficiaries aged 40-79 years since 1994 for 11 years. We used Cox proportional hazard models adjusted for possible confounding factors. We also performed propensity for use of the health check-up matched cohort analyses. Results: Compared to non-screenees, multiple-adjusted hazard ratios (95% confidence intervals) for all-cause and cardiovascular disease mortality among screenees were 0.74 (0.62-0.88) and 0.65 (0.44-0.95) for men and 0.69 (0.52-0.91) and 0.61 (0.36-1.04) for women, respectively. These relations were also observed when we used propensity matched cohort analyses. Conclusion: This is the first study to show that mortality rates are lower among screenees than non-screenees in Japanese health check-ups when propensity matched cohort analyses were used for adjusting confounding factors. Further prospective studies, including randomized controlled trials, are required to confirm whether screening lowers mortality.
| Original language | English |
|---|---|
| Pages (from-to) | 397-402 |
| Number of pages | 6 |
| Journal | Preventive Medicine |
| Volume | 51 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 01-11-2010 |
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All Science Journal Classification (ASJC) codes
- Epidemiology
- Public Health, Environmental and Occupational Health
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Participation in health check-ups and mortality using propensity score matched cohort analyses. / Hozawa, Atsushi; Kuriyama, Shinichi; Watanabe, Ikue; Kakizaki, Masako; Ohmori-Matsuda, Kaori; Sone, Toshimasa; Nagai, Masato; Sugawara, Yumi; Nitta, Akemi; Li, Qiang; Ohkubo, Takayoshi; Murakami, Yoshitaka; Tsuji, Ichiro.
In: Preventive Medicine, Vol. 51, No. 5, 01.11.2010, p. 397-402.Research output: Contribution to journal › Article
TY - JOUR
T1 - Participation in health check-ups and mortality using propensity score matched cohort analyses
AU - Hozawa, Atsushi
AU - Kuriyama, Shinichi
AU - Watanabe, Ikue
AU - Kakizaki, Masako
AU - Ohmori-Matsuda, Kaori
AU - Sone, Toshimasa
AU - Nagai, Masato
AU - Sugawara, Yumi
AU - Nitta, Akemi
AU - Li, Qiang
AU - Ohkubo, Takayoshi
AU - Murakami, Yoshitaka
AU - Tsuji, Ichiro
PY - 2010/11/1
Y1 - 2010/11/1
N2 - Objective: All Japanese aged ≥40 years are eligible for free annual health check-ups including blood pressure and cholesterol measurements. It is well known that health check-up screenees are more likely to have healthy lifestyles and better health conditions than non-screenees. Therefore, controlling these factors is required to investigate whether screenees have a lower mortality risk than non-screenees independent of their lifestyles or health conditions. Methods: We followed 48,775 Japanese National Health Insurance beneficiaries aged 40-79 years since 1994 for 11 years. We used Cox proportional hazard models adjusted for possible confounding factors. We also performed propensity for use of the health check-up matched cohort analyses. Results: Compared to non-screenees, multiple-adjusted hazard ratios (95% confidence intervals) for all-cause and cardiovascular disease mortality among screenees were 0.74 (0.62-0.88) and 0.65 (0.44-0.95) for men and 0.69 (0.52-0.91) and 0.61 (0.36-1.04) for women, respectively. These relations were also observed when we used propensity matched cohort analyses. Conclusion: This is the first study to show that mortality rates are lower among screenees than non-screenees in Japanese health check-ups when propensity matched cohort analyses were used for adjusting confounding factors. Further prospective studies, including randomized controlled trials, are required to confirm whether screening lowers mortality.
AB - Objective: All Japanese aged ≥40 years are eligible for free annual health check-ups including blood pressure and cholesterol measurements. It is well known that health check-up screenees are more likely to have healthy lifestyles and better health conditions than non-screenees. Therefore, controlling these factors is required to investigate whether screenees have a lower mortality risk than non-screenees independent of their lifestyles or health conditions. Methods: We followed 48,775 Japanese National Health Insurance beneficiaries aged 40-79 years since 1994 for 11 years. We used Cox proportional hazard models adjusted for possible confounding factors. We also performed propensity for use of the health check-up matched cohort analyses. Results: Compared to non-screenees, multiple-adjusted hazard ratios (95% confidence intervals) for all-cause and cardiovascular disease mortality among screenees were 0.74 (0.62-0.88) and 0.65 (0.44-0.95) for men and 0.69 (0.52-0.91) and 0.61 (0.36-1.04) for women, respectively. These relations were also observed when we used propensity matched cohort analyses. Conclusion: This is the first study to show that mortality rates are lower among screenees than non-screenees in Japanese health check-ups when propensity matched cohort analyses were used for adjusting confounding factors. Further prospective studies, including randomized controlled trials, are required to confirm whether screening lowers mortality.
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U2 - 10.1016/j.ypmed.2010.08.017
DO - 10.1016/j.ypmed.2010.08.017
M3 - Article
VL - 51
SP - 397
EP - 402
JO - Preventive Medicine
JF - Preventive Medicine
SN - 0091-7435
IS - 5
ER -