Perfusion and ventilation isotope lung scans in constrictive bronchiolitis obliterans. A series of three cases

Yoshinori Hasegawa, Kazuyoshi Imaizumi, Yoshitaka Sekido, Yoshitsugu Iinuma, Tsutomu Kawabe, Naozumi Hashimoto, Kaoru Shimokata

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Constrictive bronchiolitis obliterans (BO) has been defined as a syndrome of airflow limitation due to bronchiolar and peribronchiolar inflammation and fibrosis. However, chest roentgenograms are frequently normal, and alternative radiographic evaluation or other manifestations of the disease would be required. Here we report three patients with BO. We performed a technetium-99m-labeled macroaggregate human albumin lung perfusion scan and a ventilation scan using krypton-81m. We observed multiple matched defects in the perfusion and ventilation scans in these patients, which represent narrowing or obliteration of the bronchiolar lumen and its adjacent pulmonary arteriole. We propose that this is a useful diagnostic approach for an imaging study of BO.

Original languageEnglish
Pages (from-to)550-555
Number of pages6
JournalRespiration
Volume69
Issue number6
DOIs
Publication statusPublished - 12-12-2002
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

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