Plasma medical science for cancer therapy: Toward cancer therapy using nonthermal atmospheric pressure plasma

Hiromasa Tanaka; Masaaki Mizuno; Kenji Ishikawa; Keigo Takeda; Kae Nakamura; Fumi Utsumi; Hiroaki Kajiyama; Hiroyuki Kano; Yasumasa Okazaki; Shinnya Toyokuni; Shoichi Maruyama; Fumitaka Kikkawa; Masaru Hori

doi:10.1109/TPS.2014.2353659

Plasma medical science for cancer therapy: Toward cancer therapy using nonthermal atmospheric pressure plasma

Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Keigo Takeda, Kae Nakamura, Fumi Utsumi, Hiroaki Kajiyama, Hiroyuki Kano, Yasumasa Okazaki, Shinnya Toyokuni, Shoichi Maruyama, Fumitaka Kikkawa, Masaru Hori

Research output: Contribution to journal › Article › peer-review

98 Citations (Scopus)

Abstract

We have been developing novel ultrahigh density atmospheric pressure plasma sources and succeeded in the selective killing ovarian cancer cells against normal ones. Furthermore, we have found out the plasma-activated medium (PAM) also killed glioblastoma brain tumor cells selectively against normal ones and the chemical products in the PAM have long lifetime healing effects. To clarify the mechanism, interactions of plasma with the organism and the medium where the organism belongs were investigated on the viewpoint of intracellular molecular mechanism.

Original language	English
Article number	6978074
Pages (from-to)	3760-3764
Number of pages	5
Journal	IEEE Transactions on Plasma Science
Volume	42
Issue number	12
DOIs	https://doi.org/10.1109/TPS.2014.2353659
Publication status	Published - 01-12-2014
Externally published	Yes

All Science Journal Classification (ASJC) codes

Nuclear and High Energy Physics
Condensed Matter Physics

UN SDGs

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10.1109/TPS.2014.2353659

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Tanaka, H., Mizuno, M., Ishikawa, K., Takeda, K., Nakamura, K., Utsumi, F., Kajiyama, H., Kano, H., Okazaki, Y., Toyokuni, S., Maruyama, S., Kikkawa, F., & Hori, M. (2014). Plasma medical science for cancer therapy: Toward cancer therapy using nonthermal atmospheric pressure plasma. IEEE Transactions on Plasma Science, 42(12), 3760-3764. Article 6978074. https://doi.org/10.1109/TPS.2014.2353659

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title = "Plasma medical science for cancer therapy: Toward cancer therapy using nonthermal atmospheric pressure plasma",

abstract = "We have been developing novel ultrahigh density atmospheric pressure plasma sources and succeeded in the selective killing ovarian cancer cells against normal ones. Furthermore, we have found out the plasma-activated medium (PAM) also killed glioblastoma brain tumor cells selectively against normal ones and the chemical products in the PAM have long lifetime healing effects. To clarify the mechanism, interactions of plasma with the organism and the medium where the organism belongs were investigated on the viewpoint of intracellular molecular mechanism.",

keywords = "Cancer therapy, Plasma-activated medium, non-thermal atmospheric pressure plasma",

author = "Hiromasa Tanaka and Masaaki Mizuno and Kenji Ishikawa and Keigo Takeda and Kae Nakamura and Fumi Utsumi and Hiroaki Kajiyama and Hiroyuki Kano and Yasumasa Okazaki and Shinnya Toyokuni and Shoichi Maruyama and Fumitaka Kikkawa and Masaru Hori",

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doi = "10.1109/TPS.2014.2353659",

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Tanaka, H, Mizuno, M, Ishikawa, K, Takeda, K, Nakamura, K, Utsumi, F, Kajiyama, H, Kano, H, Okazaki, Y, Toyokuni, S, Maruyama, S, Kikkawa, F & Hori, M 2014, 'Plasma medical science for cancer therapy: Toward cancer therapy using nonthermal atmospheric pressure plasma', IEEE Transactions on Plasma Science, vol. 42, no. 12, 6978074, pp. 3760-3764. https://doi.org/10.1109/TPS.2014.2353659

TY - JOUR

T1 - Plasma medical science for cancer therapy

T2 - Toward cancer therapy using nonthermal atmospheric pressure plasma

AU - Tanaka, Hiromasa

AU - Mizuno, Masaaki

AU - Ishikawa, Kenji

AU - Takeda, Keigo

AU - Nakamura, Kae

AU - Utsumi, Fumi

AU - Kajiyama, Hiroaki

AU - Kano, Hiroyuki

AU - Okazaki, Yasumasa

AU - Toyokuni, Shinnya

AU - Maruyama, Shoichi

AU - Kikkawa, Fumitaka

AU - Hori, Masaru

PY - 2014/12/1

Y1 - 2014/12/1

N2 - We have been developing novel ultrahigh density atmospheric pressure plasma sources and succeeded in the selective killing ovarian cancer cells against normal ones. Furthermore, we have found out the plasma-activated medium (PAM) also killed glioblastoma brain tumor cells selectively against normal ones and the chemical products in the PAM have long lifetime healing effects. To clarify the mechanism, interactions of plasma with the organism and the medium where the organism belongs were investigated on the viewpoint of intracellular molecular mechanism.

AB - We have been developing novel ultrahigh density atmospheric pressure plasma sources and succeeded in the selective killing ovarian cancer cells against normal ones. Furthermore, we have found out the plasma-activated medium (PAM) also killed glioblastoma brain tumor cells selectively against normal ones and the chemical products in the PAM have long lifetime healing effects. To clarify the mechanism, interactions of plasma with the organism and the medium where the organism belongs were investigated on the viewpoint of intracellular molecular mechanism.

KW - Cancer therapy

KW - Plasma-activated medium

KW - non-thermal atmospheric pressure plasma

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U2 - 10.1109/TPS.2014.2353659

DO - 10.1109/TPS.2014.2353659

M3 - Article

AN - SCOPUS:84919495589

SN - 0093-3813

VL - 42

SP - 3760

EP - 3764

JO - IEEE Transactions on Plasma Science

JF - IEEE Transactions on Plasma Science

IS - 12

M1 - 6978074

ER -

Plasma medical science for cancer therapy: Toward cancer therapy using nonthermal atmospheric pressure plasma

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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