TY - JOUR
T1 - Pneumonia with marked pleural effusion caused by Aspergillus infection
AU - Miyake, Fumi
AU - Yoshikawa, Tetsushi
AU - Fujita, Ayano
AU - Usui, Chie
AU - Akimoto, Shiho
AU - Tanaka, Toshio
AU - Saito, Yumiko
AU - Asano, Yoshizo
PY - 2006/2
Y1 - 2006/2
N2 - We present a case of pneumonia with marked pleural effusion caused by Aspergillus infection in a 2-year-old Japanese girl with Down's syndrome. The patient was previously diagnosed with acute myeloid leukemia, developing the pneumonia during induction treatment. Although no pathogens could be isolated from any clinical specimens, 135,000 copies/mL of Aspergillus DNA were detected in the pleural fluid using real time polymerase chain reaction. The copy numbers of DNA decreased rapidly after appropriate antifungal treatment.
AB - We present a case of pneumonia with marked pleural effusion caused by Aspergillus infection in a 2-year-old Japanese girl with Down's syndrome. The patient was previously diagnosed with acute myeloid leukemia, developing the pneumonia during induction treatment. Although no pathogens could be isolated from any clinical specimens, 135,000 copies/mL of Aspergillus DNA were detected in the pleural fluid using real time polymerase chain reaction. The copy numbers of DNA decreased rapidly after appropriate antifungal treatment.
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U2 - 10.1097/01.inf.0000200101.32809.d5
DO - 10.1097/01.inf.0000200101.32809.d5
M3 - Article
C2 - 16462306
AN - SCOPUS:32144464573
SN - 0891-3668
VL - 25
SP - 186
EP - 187
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
IS - 2
ER -
