Pneumonitis induced by ou-gon (scullcap)

Kei Takeshita; Yoshifumi Saisho; Kumi Kitamura; Noriko Kaburagi; Tomohiro Funabiki; Toshiyuki Inamura; Yoshitaka Oyamada; Koichiro Asano; Kazuhiro Yamaguchi

doi:10.2169/internalmedicine.40.764

Pneumonitis induced by ou-gon (scullcap)

Kei Takeshita, Yoshifumi Saisho, Kumi Kitamura, Noriko Kaburagi, Tomohiro Funabiki, Toshiyuki Inamura, Yoshitaka Oyamada, Koichiro Asano, Kazuhiro Yamaguchi

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

A 53-year-old Japanese man with recurrent interstitial pneumonia was referred to us. The patient had taken a traditional herb medicine, otsu-ji-to, before the onset of pneumonia. A provocation test for each herbal ingredient contained in otsu-ji-to revealed that the pneumonitis had been induced by ou-gon (scullcap). Lymphocytosis with the CD8+ T-cell subset predominance was found in the bronchoalveolar lavage fluid and lymphocytic alveolitis was noted in the transbronchial lung biopsy specimen after the provocation test. Ou-gon, or scullcap, should be included in the list of drugs with definite causal association with pneumonitis.

Original language	English
Pages (from-to)	764-768
Number of pages	5
Journal	Internal Medicine
Volume	40
Issue number	8
DOIs	https://doi.org/10.2169/internalmedicine.40.764
Publication status	Published - 08-2001
Externally published	Yes

All Science Journal Classification (ASJC) codes

Internal Medicine

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title = "Pneumonitis induced by ou-gon (scullcap)",

abstract = "A 53-year-old Japanese man with recurrent interstitial pneumonia was referred to us. The patient had taken a traditional herb medicine, otsu-ji-to, before the onset of pneumonia. A provocation test for each herbal ingredient contained in otsu-ji-to revealed that the pneumonitis had been induced by ou-gon (scullcap). Lymphocytosis with the CD8+ T-cell subset predominance was found in the bronchoalveolar lavage fluid and lymphocytic alveolitis was noted in the transbronchial lung biopsy specimen after the provocation test. Ou-gon, or scullcap, should be included in the list of drugs with definite causal association with pneumonitis.",

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T1 - Pneumonitis induced by ou-gon (scullcap)

AU - Takeshita, Kei

AU - Saisho, Yoshifumi

AU - Kitamura, Kumi

AU - Kaburagi, Noriko

AU - Funabiki, Tomohiro

AU - Inamura, Toshiyuki

AU - Oyamada, Yoshitaka

AU - Asano, Koichiro

AU - Yamaguchi, Kazuhiro

PY - 2001/8

Y1 - 2001/8

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AB - A 53-year-old Japanese man with recurrent interstitial pneumonia was referred to us. The patient had taken a traditional herb medicine, otsu-ji-to, before the onset of pneumonia. A provocation test for each herbal ingredient contained in otsu-ji-to revealed that the pneumonitis had been induced by ou-gon (scullcap). Lymphocytosis with the CD8+ T-cell subset predominance was found in the bronchoalveolar lavage fluid and lymphocytic alveolitis was noted in the transbronchial lung biopsy specimen after the provocation test. Ou-gon, or scullcap, should be included in the list of drugs with definite causal association with pneumonitis.

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JF - Internal Medicine

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Pneumonitis induced by ou-gon (scullcap)

Abstract

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