Point of Care Testing Chip for Multiple Virus Infection Detection Using LAMP

Yusuke Kimura, Masashi Ikeuchi, Yoshinori Inoue, Koji Ikuta

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Here, we developed a portable microdevice for the simple and early detection of viral infections via the loop-mediated isothermal amplification (LAMP) method, as a point-of-care testing (POCT) method. This microdevice can simultaneously check 16 species of viral infection by observing fluorescence intensity, either by the naked eye or using a smartphone photo sensor. It requires only 1% of conventional sample amounts, and can run using a small battery. We also developed a simple system for simultaneously applying samples to 16 wells. Basic performance was verified using a dengue virus detection experiment, and the specific reaction was successfully confirmed following application of dengue virus RNA samples.

Original languageEnglish
Title of host publication2019 IEEE 32nd International Conference on Micro Electro Mechanical Systems, MEMS 2019
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages83-86
Number of pages4
ISBN (Electronic)9781728116105
DOIs
Publication statusPublished - 01-2019
Externally publishedYes
Event32nd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2019 - Seoul, Korea, Republic of
Duration: 27-01-201931-01-2019

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume2019-January
ISSN (Print)1084-6999

Conference

Conference32nd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2019
Country/TerritoryKorea, Republic of
CitySeoul
Period27-01-1931-01-19

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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