Portopulmonary hypertension: Hemodynamics, pulmonary angiography, and configuration of the heart

Masahito Sakuma; Shinko Souma; Osamu Kitamukai; Jun Demachi; Tohru Takahashi; Jun Suzuki; Jun Nawata; Kouichiro Sugimura; Minako Oikawa; Kenya Saji; Tomohiro Tada; Shigefumi Fukui; Yutaka Kagaya; Jun Watanabe; Kunio Shirato

doi:10.1253/circj.69.1386

Portopulmonary hypertension: Hemodynamics, pulmonary angiography, and configuration of the heart

Masahito Sakuma, Shinko Souma, Osamu Kitamukai, Jun Demachi, Tohru Takahashi, Jun Suzuki, Jun Nawata, Kouichiro Sugimura, Minako Oikawa, Kenya Saji, Tomohiro Tada, Shigefumi Fukui, Yutaka Kagaya, Jun Watanabe, Kunio Shirato

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Background: The goal of the present study was to examine the cardiac configuration and pulmonary vascular changes in patients with portopulmonary hypertension (PPHTN) and compare them with those of idiopathic pulmonary arterial hypertension (IPAH). Methods and Results: The subjects were 10 patients with PPHTN and 18 with IPAH. In PPHTN, the increases in the right ventricular end-diastolic volume index (89±19 vs 128±50ml/m²; p=0.04), right end-systolic volume index (50±19 vs 95±47ml/m ²; p=0.02) and right ventricular mass index (47±18g/m ² vs 79±31; p=0.04) were low compared with IPAH. The decrease in the right ventricular ejection fraction was also low in PPHTN (45±10 vs 28±13%; p=0.01). The degree of sparse arborization and abrupt narrowing on wedged pulmonary angiography was moderate in PPHTN compared with IPAH. In PPHTN, the proximal pulmonary arteries were dilated near the segmental arteries, which were narrow in IPAH. Conclusion: Changes in the configuration of the heart were moderate in PPHTN compared with those in IPAH. The degree of sparse arborization and abrupt narrowing were also moderate in PPHTN.

Original language	English
Pages (from-to)	1386-1393
Number of pages	8
Journal	Circulation Journal
Volume	69
Issue number	11
DOIs	https://doi.org/10.1253/circj.69.1386
Publication status	Published - 2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine

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10.1253/circj.69.1386

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Sakuma, M., Souma, S., Kitamukai, O., Demachi, J., Takahashi, T., Suzuki, J., Nawata, J., Sugimura, K., Oikawa, M., Saji, K., Tada, T., Fukui, S., Kagaya, Y., Watanabe, J., & Shirato, K. (2005). Portopulmonary hypertension: Hemodynamics, pulmonary angiography, and configuration of the heart. Circulation Journal, 69(11), 1386-1393. https://doi.org/10.1253/circj.69.1386

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title = "Portopulmonary hypertension: Hemodynamics, pulmonary angiography, and configuration of the heart",

abstract = "Background: The goal of the present study was to examine the cardiac configuration and pulmonary vascular changes in patients with portopulmonary hypertension (PPHTN) and compare them with those of idiopathic pulmonary arterial hypertension (IPAH). Methods and Results: The subjects were 10 patients with PPHTN and 18 with IPAH. In PPHTN, the increases in the right ventricular end-diastolic volume index (89±19 vs 128±50ml/m2; p=0.04), right end-systolic volume index (50±19 vs 95±47ml/m 2; p=0.02) and right ventricular mass index (47±18g/m 2 vs 79±31; p=0.04) were low compared with IPAH. The decrease in the right ventricular ejection fraction was also low in PPHTN (45±10 vs 28±13%; p=0.01). The degree of sparse arborization and abrupt narrowing on wedged pulmonary angiography was moderate in PPHTN compared with IPAH. In PPHTN, the proximal pulmonary arteries were dilated near the segmental arteries, which were narrow in IPAH. Conclusion: Changes in the configuration of the heart were moderate in PPHTN compared with those in IPAH. The degree of sparse arborization and abrupt narrowing were also moderate in PPHTN.",

author = "Masahito Sakuma and Shinko Souma and Osamu Kitamukai and Jun Demachi and Tohru Takahashi and Jun Suzuki and Jun Nawata and Kouichiro Sugimura and Minako Oikawa and Kenya Saji and Tomohiro Tada and Shigefumi Fukui and Yutaka Kagaya and Jun Watanabe and Kunio Shirato",

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doi = "10.1253/circj.69.1386",

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T1 - Portopulmonary hypertension

T2 - Hemodynamics, pulmonary angiography, and configuration of the heart

AU - Sakuma, Masahito

AU - Souma, Shinko

AU - Kitamukai, Osamu

AU - Demachi, Jun

AU - Takahashi, Tohru

AU - Suzuki, Jun

AU - Nawata, Jun

AU - Sugimura, Kouichiro

AU - Oikawa, Minako

AU - Saji, Kenya

AU - Tada, Tomohiro

AU - Fukui, Shigefumi

AU - Kagaya, Yutaka

AU - Watanabe, Jun

AU - Shirato, Kunio

PY - 2005

Y1 - 2005

N2 - Background: The goal of the present study was to examine the cardiac configuration and pulmonary vascular changes in patients with portopulmonary hypertension (PPHTN) and compare them with those of idiopathic pulmonary arterial hypertension (IPAH). Methods and Results: The subjects were 10 patients with PPHTN and 18 with IPAH. In PPHTN, the increases in the right ventricular end-diastolic volume index (89±19 vs 128±50ml/m2; p=0.04), right end-systolic volume index (50±19 vs 95±47ml/m 2; p=0.02) and right ventricular mass index (47±18g/m 2 vs 79±31; p=0.04) were low compared with IPAH. The decrease in the right ventricular ejection fraction was also low in PPHTN (45±10 vs 28±13%; p=0.01). The degree of sparse arborization and abrupt narrowing on wedged pulmonary angiography was moderate in PPHTN compared with IPAH. In PPHTN, the proximal pulmonary arteries were dilated near the segmental arteries, which were narrow in IPAH. Conclusion: Changes in the configuration of the heart were moderate in PPHTN compared with those in IPAH. The degree of sparse arborization and abrupt narrowing were also moderate in PPHTN.

AB - Background: The goal of the present study was to examine the cardiac configuration and pulmonary vascular changes in patients with portopulmonary hypertension (PPHTN) and compare them with those of idiopathic pulmonary arterial hypertension (IPAH). Methods and Results: The subjects were 10 patients with PPHTN and 18 with IPAH. In PPHTN, the increases in the right ventricular end-diastolic volume index (89±19 vs 128±50ml/m2; p=0.04), right end-systolic volume index (50±19 vs 95±47ml/m 2; p=0.02) and right ventricular mass index (47±18g/m 2 vs 79±31; p=0.04) were low compared with IPAH. The decrease in the right ventricular ejection fraction was also low in PPHTN (45±10 vs 28±13%; p=0.01). The degree of sparse arborization and abrupt narrowing on wedged pulmonary angiography was moderate in PPHTN compared with IPAH. In PPHTN, the proximal pulmonary arteries were dilated near the segmental arteries, which were narrow in IPAH. Conclusion: Changes in the configuration of the heart were moderate in PPHTN compared with those in IPAH. The degree of sparse arborization and abrupt narrowing were also moderate in PPHTN.

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Portopulmonary hypertension: Hemodynamics, pulmonary angiography, and configuration of the heart

Abstract

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