Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection

Tadashi Yoshida, Shigenori Homma, Susumu Shibasaki, Tatsushi Shimokuni, Hideyasu Sakihama, Norihiko Takahashi, Hideki Kawamura, Akinobu Taketomi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Purpose: Effective postoperative analgesia is essential to a patient’s recovery after laparoscopic colon resection (LCR). We introduce a new analgesic protocol using fentanyl plus celecoxib following LCR. Methods: The subjects of this retrospective comparative study were 137 patients who underwent LCR, 63 of whom were treated with 72 h of epidural anesthesia (group E), and 74 of whom were treated with 24 h of fentanyl intravenous injection followed by 7 days of oral celecoxib (group FC). We evaluated the safety and efficacy of this new protocol. Results: The combination of fentanyl and celecoxib maintained a low postoperative pain score (<1.5, evaluated by the FACES Pain Scale) and reduced the need for rescue analgesic drugs for 7 days (groups E vs. FC: 5.39 ± 3.77 vs. 2.79 ± 2.92, p < 0.001). The postoperative hospital stay was almost equal for the two groups (E vs. FC: 11.1 ± 4.5 vs. 10.3 ± 4.8 days, p = 0.315). The operating room stay other than for surgery was significantly shorter for group FC (E vs. FC: 128.7 ± 30.5 vs. 107.2 ± 17.0 min, p < 0.001). Neither group experienced complications, apart from one group FC patient, who suffered transient nausea and vertigo. Conclusions: The new analgesic protocol using fentanyl plus celecoxib is an effective and time-saving strategy for LCR.

Original languageEnglish
Pages (from-to)174-181
Number of pages8
JournalSurgery Today
Volume47
Issue number2
DOIs
Publication statusPublished - 01-02-2017

All Science Journal Classification (ASJC) codes

  • Surgery

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    Yoshida, T., Homma, S., Shibasaki, S., Shimokuni, T., Sakihama, H., Takahashi, N., Kawamura, H., & Taketomi, A. (2017). Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection. Surgery Today, 47(2), 174-181. https://doi.org/10.1007/s00595-016-1356-y