Postresection autopsy findings in patients with cancer of the main hepatic duct junction

Toshiharu Tsuzuki, Atsushi Sugioka, Masakazu Ueda, Shuhei Iida, Izumi Nakanishi, Shigeru Kuramochi

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Extensive resection of the bile ducts combined with hepatic resection is the procedure of choice for carcinoma of the main hepatic duct junction. Currently this procedure is done without great risk, and increasing long‐term survival is now the issue. For this purpose, it is necessary to elucidate the biologic properties of the cancer to take reasonable measures. Autopsy findings of patients who died of recurrence may offer a reliable guide. Autopsy findings were studied in 14 patients: eight who had undergone curative resection and six who had received noncurative resection. Cancer recurred at the liver hilum with invasion into adjacent organs. Peritoneal dissemination and lymph node metastases were infrequent. These were common findings in both curative and noncurative resection groups. Cancer cells in the connective tissue of the hepatoduodenal ligament may play a major role in recurrence.

Original languageEnglish
Pages (from-to)3010-3013
Number of pages4
JournalCancer
Volume67
Issue number12
DOIs
Publication statusPublished - 15-06-1991
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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