TY - JOUR
T1 - Precancerous conditions of biliary tract cancer in patients with pancreaticobiliary malfunction
T2 - Reappraisal of nationwide survey in Japan
AU - Hasumi, Akitake
AU - Matsui, Hideo
AU - Sugioka, Atsushi
AU - Uyama, Ichiro
AU - Komoki, Yoshiyuki
AU - Fujita, Junko
AU - Aoki, Hakuo
PY - 2000
Y1 - 2000
N2 - It is widely known that pancreaticobiliary maljunction (PBM), an anomalous arrangement of the pancreaticobiliary ductal system, is frequently associated with biliary tract cancer in patients with or without bile duct dilatation. In 1985. we surveyed patients with PBM who had been operated on at 133 Japanese institutions. A close relationship was shown between biliary tract carcinogenesis and PBM, according to the type of maljunction and age distribution: PBM patients with cystic dilatation had a high risk of bile duct cancer, even in those who were young (aged less than 20 years); the incidence of gallbladder cancer increased markedly in PBM patients over 40 years old with cystic dilatation, while it gradually increased with age in the PBM patients without cystic dilatation. Therefore, we recommend surgical treatment lor patients with PBM even if they have no symptoms.
AB - It is widely known that pancreaticobiliary maljunction (PBM), an anomalous arrangement of the pancreaticobiliary ductal system, is frequently associated with biliary tract cancer in patients with or without bile duct dilatation. In 1985. we surveyed patients with PBM who had been operated on at 133 Japanese institutions. A close relationship was shown between biliary tract carcinogenesis and PBM, according to the type of maljunction and age distribution: PBM patients with cystic dilatation had a high risk of bile duct cancer, even in those who were young (aged less than 20 years); the incidence of gallbladder cancer increased markedly in PBM patients over 40 years old with cystic dilatation, while it gradually increased with age in the PBM patients without cystic dilatation. Therefore, we recommend surgical treatment lor patients with PBM even if they have no symptoms.
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U2 - 10.1007/s005340070003
DO - 10.1007/s005340070003
M3 - Article
C2 - 11180886
AN - SCOPUS:0034575953
SN - 0944-1166
VL - 7
SP - 551
EP - 555
JO - Journal of Hepato-Biliary-Pancreatic Surgery
JF - Journal of Hepato-Biliary-Pancreatic Surgery
IS - 6
ER -