Predictive value of acetylcholine stimulation testing for oligohidrosis caused by zonisamide

Akihisa Okumura; Naoko Ishihara; Toru Kato; Fumio Hayakawa; Kuniyoshi Kuno; Kazuyoshi Watanabe

doi:10.1016/S0887-8994(00)00144-2

Predictive value of acetylcholine stimulation testing for oligohidrosis caused by zonisamide

Akihisa Okumura
, Naoko Ishihara
, Toru Kato
, Fumio Hayakawa
, Kuniyoshi Kuno
, Kazuyoshi Watanabe

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

We studied 16 patients for whom zonisamide was newly prescribed. Acetylcholine stimulation testing was performed about 1 month after zonisamide was initiated. Oligohidrosis occurred in none of the four with a normal response and in four of the 12 with a decreased response. Acetylcholine stimulation testing predicted oligohidrosis with a sensitivity of 1 and a false-positive rate of 0.67. The acetylcholine stimulation test was sensitive in detecting oligohidrosis caused by zonisamide, although the false-positive rate was high. (C) 2000 by Elsevier Science Inc.

Original language	English
Pages (from-to)	59-61
Number of pages	3
Journal	Pediatric Neurology
Volume	23
Issue number	1
DOIs	https://doi.org/10.1016/S0887-8994(00)00144-2
Publication status	Published - 07-2000
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health
Neurology
Developmental Neuroscience
Clinical Neurology

Access to Document

10.1016/S0887-8994(00)00144-2

Cite this

@article{6a832d933ad24b4dbbb2fa80c7f9885f,

title = "Predictive value of acetylcholine stimulation testing for oligohidrosis caused by zonisamide",

abstract = "We studied 16 patients for whom zonisamide was newly prescribed. Acetylcholine stimulation testing was performed about 1 month after zonisamide was initiated. Oligohidrosis occurred in none of the four with a normal response and in four of the 12 with a decreased response. Acetylcholine stimulation testing predicted oligohidrosis with a sensitivity of 1 and a false-positive rate of 0.67. The acetylcholine stimulation test was sensitive in detecting oligohidrosis caused by zonisamide, although the false-positive rate was high. (C) 2000 by Elsevier Science Inc.",

author = "Akihisa Okumura and Naoko Ishihara and Toru Kato and Fumio Hayakawa and Kuniyoshi Kuno and Kazuyoshi Watanabe",

year = "2000",

month = jul,

doi = "10.1016/S0887-8994(00)00144-2",

language = "English",

volume = "23",

pages = "59--61",

journal = "Pediatric Neurology",

issn = "0887-8994",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Predictive value of acetylcholine stimulation testing for oligohidrosis caused by zonisamide

AU - Okumura, Akihisa

AU - Ishihara, Naoko

AU - Kato, Toru

AU - Hayakawa, Fumio

AU - Kuno, Kuniyoshi

AU - Watanabe, Kazuyoshi

PY - 2000/7

Y1 - 2000/7

N2 - We studied 16 patients for whom zonisamide was newly prescribed. Acetylcholine stimulation testing was performed about 1 month after zonisamide was initiated. Oligohidrosis occurred in none of the four with a normal response and in four of the 12 with a decreased response. Acetylcholine stimulation testing predicted oligohidrosis with a sensitivity of 1 and a false-positive rate of 0.67. The acetylcholine stimulation test was sensitive in detecting oligohidrosis caused by zonisamide, although the false-positive rate was high. (C) 2000 by Elsevier Science Inc.

AB - We studied 16 patients for whom zonisamide was newly prescribed. Acetylcholine stimulation testing was performed about 1 month after zonisamide was initiated. Oligohidrosis occurred in none of the four with a normal response and in four of the 12 with a decreased response. Acetylcholine stimulation testing predicted oligohidrosis with a sensitivity of 1 and a false-positive rate of 0.67. The acetylcholine stimulation test was sensitive in detecting oligohidrosis caused by zonisamide, although the false-positive rate was high. (C) 2000 by Elsevier Science Inc.

UR - https://www.scopus.com/pages/publications/0033839430

UR - https://www.scopus.com/pages/publications/0033839430#tab=citedBy

U2 - 10.1016/S0887-8994(00)00144-2

DO - 10.1016/S0887-8994(00)00144-2

M3 - Article

C2 - 10963972

AN - SCOPUS:0033839430

SN - 0887-8994

VL - 23

SP - 59

EP - 61

JO - Pediatric Neurology

JF - Pediatric Neurology

IS - 1

ER -

Predictive value of acetylcholine stimulation testing for oligohidrosis caused by zonisamide

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this