TY - JOUR
T1 - Predictors of survival in patients with chronic hypercapnic respiratory failure receiving domiciliary NPPV
AU - Takada, Kazuto
AU - Matsumoto, Shuuichi
AU - Hiramatsu, Tetsuo
AU - Kojima, Eiji
AU - Watanabe, Hiroaki
AU - Sizu, Masato
AU - Okachi, Shoutarou
AU - Ninomiya, Kiyoko
PY - 2008/8
Y1 - 2008/8
N2 - Fifty-four cases (36 men) with chronic hypercapnic respiratory failure were prescribed domiciliary NPPV during 9 years. COPD (26 patients) and sequelae of tuberclosis (16 patients) were the major primary diseases. At the initiation of NPPV, the age was 71.2 +/- 7.3 years-old (mean +/- standard deviation) and PaCO2 was 76.7 +/- 16.2Torr. Overall, the 1-year and 5-year survival rates were 63.8% and 26.0%, respectively. Multivariate analysis identified BMI (body mass index) (hazzard ratio : 0.837, p = 0.020) and the number of days of hospitalization during 1 year before NPPV (hazzard ratio: 1.013, p = 0.016) as predictors of survival. Patients with frequent hospitalization for exacerbation or with malnutrition had poor prognosis, so comprehensive supports aimed to improve general status are needed for patients with chronic respiratory failure received domiciliary NPPV.
AB - Fifty-four cases (36 men) with chronic hypercapnic respiratory failure were prescribed domiciliary NPPV during 9 years. COPD (26 patients) and sequelae of tuberclosis (16 patients) were the major primary diseases. At the initiation of NPPV, the age was 71.2 +/- 7.3 years-old (mean +/- standard deviation) and PaCO2 was 76.7 +/- 16.2Torr. Overall, the 1-year and 5-year survival rates were 63.8% and 26.0%, respectively. Multivariate analysis identified BMI (body mass index) (hazzard ratio : 0.837, p = 0.020) and the number of days of hospitalization during 1 year before NPPV (hazzard ratio: 1.013, p = 0.016) as predictors of survival. Patients with frequent hospitalization for exacerbation or with malnutrition had poor prognosis, so comprehensive supports aimed to improve general status are needed for patients with chronic respiratory failure received domiciliary NPPV.
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M3 - Article
C2 - 18788429
AN - SCOPUS:54049092462
SN - 1343-3490
VL - 46
SP - 614
EP - 619
JO - Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
JF - Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
IS - 8
ER -
