Predictors of survival in patients with chronic hypercapnic respiratory failure receiving domiciliary NPPV

Kazuto Takada; Shuuichi Matsumoto; Tetsuo Hiramatsu; Eiji Kojima; Hiroaki Watanabe; Masato Sizu; Shoutarou Okachi; Kiyoko Ninomiya

Predictors of survival in patients with chronic hypercapnic respiratory failure receiving domiciliary NPPV

Kazuto Takada
, Shuuichi Matsumoto
, Tetsuo Hiramatsu
, Eiji Kojima
, Hiroaki Watanabe
, Masato Sizu
, Shoutarou Okachi
, Kiyoko Ninomiya

Research output: Contribution to journal › Article › peer-review

Abstract

Fifty-four cases (36 men) with chronic hypercapnic respiratory failure were prescribed domiciliary NPPV during 9 years. COPD (26 patients) and sequelae of tuberclosis (16 patients) were the major primary diseases. At the initiation of NPPV, the age was 71.2 +/- 7.3 years-old (mean +/- standard deviation) and PaCO2 was 76.7 +/- 16.2Torr. Overall, the 1-year and 5-year survival rates were 63.8% and 26.0%, respectively. Multivariate analysis identified BMI (body mass index) (hazzard ratio : 0.837, p = 0.020) and the number of days of hospitalization during 1 year before NPPV (hazzard ratio: 1.013, p = 0.016) as predictors of survival. Patients with frequent hospitalization for exacerbation or with malnutrition had poor prognosis, so comprehensive supports aimed to improve general status are needed for patients with chronic respiratory failure received domiciliary NPPV.

Original language	English
Pages (from-to)	614-619
Number of pages	6
Journal	Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society
Volume	46
Issue number	8
Publication status	Published - 08-2008
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 2 Zero Hunger

All Science Journal Classification (ASJC) codes

General Medicine

Cite this

@article{da737d8dda0f4b489b8c3e8a6c4884b5,

title = "Predictors of survival in patients with chronic hypercapnic respiratory failure receiving domiciliary NPPV",

abstract = "Fifty-four cases (36 men) with chronic hypercapnic respiratory failure were prescribed domiciliary NPPV during 9 years. COPD (26 patients) and sequelae of tuberclosis (16 patients) were the major primary diseases. At the initiation of NPPV, the age was 71.2 +/- 7.3 years-old (mean +/- standard deviation) and PaCO2 was 76.7 +/- 16.2Torr. Overall, the 1-year and 5-year survival rates were 63.8\% and 26.0\%, respectively. Multivariate analysis identified BMI (body mass index) (hazzard ratio : 0.837, p = 0.020) and the number of days of hospitalization during 1 year before NPPV (hazzard ratio: 1.013, p = 0.016) as predictors of survival. Patients with frequent hospitalization for exacerbation or with malnutrition had poor prognosis, so comprehensive supports aimed to improve general status are needed for patients with chronic respiratory failure received domiciliary NPPV.",

author = "Kazuto Takada and Shuuichi Matsumoto and Tetsuo Hiramatsu and Eiji Kojima and Hiroaki Watanabe and Masato Sizu and Shoutarou Okachi and Kiyoko Ninomiya",

year = "2008",

month = aug,

language = "English",

volume = "46",

pages = "614--619",

journal = "Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society",

issn = "1343-3490",

publisher = "Nihon Kokyuki Gakkai",

number = "8",

}

TY - JOUR

T1 - Predictors of survival in patients with chronic hypercapnic respiratory failure receiving domiciliary NPPV

AU - Takada, Kazuto

AU - Matsumoto, Shuuichi

AU - Hiramatsu, Tetsuo

AU - Kojima, Eiji

AU - Watanabe, Hiroaki

AU - Sizu, Masato

AU - Okachi, Shoutarou

AU - Ninomiya, Kiyoko

PY - 2008/8

Y1 - 2008/8

N2 - Fifty-four cases (36 men) with chronic hypercapnic respiratory failure were prescribed domiciliary NPPV during 9 years. COPD (26 patients) and sequelae of tuberclosis (16 patients) were the major primary diseases. At the initiation of NPPV, the age was 71.2 +/- 7.3 years-old (mean +/- standard deviation) and PaCO2 was 76.7 +/- 16.2Torr. Overall, the 1-year and 5-year survival rates were 63.8% and 26.0%, respectively. Multivariate analysis identified BMI (body mass index) (hazzard ratio : 0.837, p = 0.020) and the number of days of hospitalization during 1 year before NPPV (hazzard ratio: 1.013, p = 0.016) as predictors of survival. Patients with frequent hospitalization for exacerbation or with malnutrition had poor prognosis, so comprehensive supports aimed to improve general status are needed for patients with chronic respiratory failure received domiciliary NPPV.

AB - Fifty-four cases (36 men) with chronic hypercapnic respiratory failure were prescribed domiciliary NPPV during 9 years. COPD (26 patients) and sequelae of tuberclosis (16 patients) were the major primary diseases. At the initiation of NPPV, the age was 71.2 +/- 7.3 years-old (mean +/- standard deviation) and PaCO2 was 76.7 +/- 16.2Torr. Overall, the 1-year and 5-year survival rates were 63.8% and 26.0%, respectively. Multivariate analysis identified BMI (body mass index) (hazzard ratio : 0.837, p = 0.020) and the number of days of hospitalization during 1 year before NPPV (hazzard ratio: 1.013, p = 0.016) as predictors of survival. Patients with frequent hospitalization for exacerbation or with malnutrition had poor prognosis, so comprehensive supports aimed to improve general status are needed for patients with chronic respiratory failure received domiciliary NPPV.

UR - https://www.scopus.com/pages/publications/54049092462

UR - https://www.scopus.com/pages/publications/54049092462#tab=citedBy

M3 - Article

C2 - 18788429

AN - SCOPUS:54049092462

SN - 1343-3490

VL - 46

SP - 614

EP - 619

JO - Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society

JF - Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society

IS - 8

ER -

Predictors of survival in patients with chronic hypercapnic respiratory failure receiving domiciliary NPPV

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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