Preliminary results of stereotactic radiotherapy for spinal lesions using the novalis system

Yoshimasa Mori, Chisa Hashizume, Yuta Shibamoto, Tatsuya Kobayashi, Naoki Hayashi, Natsuo Tomita, Jun Yoshid

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Aims: We report our preliminary experience of treating spinal lesions using the Novalis stereotactic radiotherapy (SRT) system. Methods: We treated 36 spinal lesions in 30 patients including 29 metastases in 23 patients, 6 primary spinal tumors, and 1 arteriovenous malformation. Most tumors were encompassed by the 90-95% isodose line. Dose was prescribed at the 100% isodose, generally giving 30-40 Gy in 10 fractions or 25-32.5 Gy in 5 fractions. Results: The median follow-up time after SRT was 3.5 months (range 3 weeks to 10 months). Eight patients died after SRT from primary cancers or systemic disease. No complications due to SRT were observed during the follow-up period. Eight patients with intractable radiating pain had partial or complete pain relief. All 4 patients with neurological deficits had partial or complete improvement during the follow-up period of 2-5 months. Of 19 metastases with imaging follow-up, 94% were controlled and 58% shrank or disappeared. Two spinal meningioma patients were stable for 2 and 6 months after SRT. Conclusions: Our observations suggest that SRT as prescribed in patients with various spinal lesions is well tolerated and with little to no significant morbidity. The authors await long-term follow-up data to determine late complications, tumor control, and nidus obliteration rates.

Original languageEnglish
Title of host publicationRadiosurgery
Subtitle of host publication8th International Stereotactic Radiosurgery Society Meeting, San Francisco, June 2007
Pages378-383
Number of pages6
DOIs
Publication statusPublished - 2010

Publication series

NameRadiosurgery
Volume7
ISSN (Print)1024-2651
ISSN (Electronic)1662-3940

All Science Journal Classification (ASJC) codes

  • Surgery
  • Radiology Nuclear Medicine and imaging

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