Preliminary study of time maximum intensity projection computed tomography imaging for the detection of early ischemic change in patient with acute ischemic stroke

Kazuhiro Murayama, Shigetaka Suzuki, Ryo Matsukiyo, Akinori Takenaka, Motoharu Hayakawa, Takashi Tsutsumi, Kenji Fujii, Kazuhiro Katada, Hiroshi Toyama

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Noncontrast computed tomography (NCCT) has been used for the detection of early ischemic change (EIC); however, correct interpretation of NCCT findings requires much clinical experience. This study aimed to assess the accuracy of time maximum intensity projection computed tomography technique (tMIP), which reflects the maximum value for the time phase direction from the dynamic volume data for each projected plane, for detection of EIC, against that of NCCT. Retrospective review of NCCT, cerebral blood volume in CT perfusion (CTP-CBV), and tMIP of 186 lesions from 280 regions evaluated by Alberta Stroke Program Early CT Score (ASPECTS) in 14 patients with acute middle cerebral artery stroke who had undergone whole-brain CTP using 320-row area detector CT was performed. Four radiologists reviewed EIC on NCCT, CTP-CBV, and tMIP in each ASPECTS region at onset using the continuous certainty factor method. Receiver operating characteristic analysis was performed to compare the relative performance for detection of EIC. The correlations were evaluated. tMIP-color showed the best discriminative value for detection of EIC. There were significant differences in the area under the curve for NCCT and tMIP-color, CTP-CBV (P < .05). Scatter plots of ASPECTS showed a positive significant correlation between NCCT, tMIP-gray, tMIP-color, and the follow-up study (NCCT, r = 0.32, P = .0166; tMIP-gray, r = 0.44, P = .0007; tMIP-color, r = 0.34, P = .0104). Because tMIP provides a high contrast parenchymal image with anatomical and vascular information in 1 sequential scan, it showed greater accuracy for detection of EIC and predicted the final infarct extent more accurately than NCCT based on ASPECTS.

Original languageEnglish
Article numbere9906
JournalMedicine (United States)
Volume97
Issue number9
DOIs
Publication statusPublished - 01-03-2018

Fingerprint

Stroke
Tomography
Cytidine Triphosphate
Alberta
Color
Cone-Beam Computed Tomography
Middle Cerebral Artery Infarction
ROC Curve
Area Under Curve
Blood Vessels
Perfusion
Brain

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Murayama, Kazuhiro ; Suzuki, Shigetaka ; Matsukiyo, Ryo ; Takenaka, Akinori ; Hayakawa, Motoharu ; Tsutsumi, Takashi ; Fujii, Kenji ; Katada, Kazuhiro ; Toyama, Hiroshi. / Preliminary study of time maximum intensity projection computed tomography imaging for the detection of early ischemic change in patient with acute ischemic stroke. In: Medicine (United States). 2018 ; Vol. 97, No. 9.
@article{c4d2c9e4ea0e45ad901cfe82ce8680fb,
title = "Preliminary study of time maximum intensity projection computed tomography imaging for the detection of early ischemic change in patient with acute ischemic stroke",
abstract = "Noncontrast computed tomography (NCCT) has been used for the detection of early ischemic change (EIC); however, correct interpretation of NCCT findings requires much clinical experience. This study aimed to assess the accuracy of time maximum intensity projection computed tomography technique (tMIP), which reflects the maximum value for the time phase direction from the dynamic volume data for each projected plane, for detection of EIC, against that of NCCT. Retrospective review of NCCT, cerebral blood volume in CT perfusion (CTP-CBV), and tMIP of 186 lesions from 280 regions evaluated by Alberta Stroke Program Early CT Score (ASPECTS) in 14 patients with acute middle cerebral artery stroke who had undergone whole-brain CTP using 320-row area detector CT was performed. Four radiologists reviewed EIC on NCCT, CTP-CBV, and tMIP in each ASPECTS region at onset using the continuous certainty factor method. Receiver operating characteristic analysis was performed to compare the relative performance for detection of EIC. The correlations were evaluated. tMIP-color showed the best discriminative value for detection of EIC. There were significant differences in the area under the curve for NCCT and tMIP-color, CTP-CBV (P < .05). Scatter plots of ASPECTS showed a positive significant correlation between NCCT, tMIP-gray, tMIP-color, and the follow-up study (NCCT, r = 0.32, P = .0166; tMIP-gray, r = 0.44, P = .0007; tMIP-color, r = 0.34, P = .0104). Because tMIP provides a high contrast parenchymal image with anatomical and vascular information in 1 sequential scan, it showed greater accuracy for detection of EIC and predicted the final infarct extent more accurately than NCCT based on ASPECTS.",
author = "Kazuhiro Murayama and Shigetaka Suzuki and Ryo Matsukiyo and Akinori Takenaka and Motoharu Hayakawa and Takashi Tsutsumi and Kenji Fujii and Kazuhiro Katada and Hiroshi Toyama",
year = "2018",
month = "3",
day = "1",
doi = "10.1097/MD.0000000000009906",
language = "English",
volume = "97",
journal = "Medicine (United States)",
issn = "0025-7974",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

Preliminary study of time maximum intensity projection computed tomography imaging for the detection of early ischemic change in patient with acute ischemic stroke. / Murayama, Kazuhiro; Suzuki, Shigetaka; Matsukiyo, Ryo; Takenaka, Akinori; Hayakawa, Motoharu; Tsutsumi, Takashi; Fujii, Kenji; Katada, Kazuhiro; Toyama, Hiroshi.

In: Medicine (United States), Vol. 97, No. 9, e9906, 01.03.2018.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Preliminary study of time maximum intensity projection computed tomography imaging for the detection of early ischemic change in patient with acute ischemic stroke

AU - Murayama, Kazuhiro

AU - Suzuki, Shigetaka

AU - Matsukiyo, Ryo

AU - Takenaka, Akinori

AU - Hayakawa, Motoharu

AU - Tsutsumi, Takashi

AU - Fujii, Kenji

AU - Katada, Kazuhiro

AU - Toyama, Hiroshi

PY - 2018/3/1

Y1 - 2018/3/1

N2 - Noncontrast computed tomography (NCCT) has been used for the detection of early ischemic change (EIC); however, correct interpretation of NCCT findings requires much clinical experience. This study aimed to assess the accuracy of time maximum intensity projection computed tomography technique (tMIP), which reflects the maximum value for the time phase direction from the dynamic volume data for each projected plane, for detection of EIC, against that of NCCT. Retrospective review of NCCT, cerebral blood volume in CT perfusion (CTP-CBV), and tMIP of 186 lesions from 280 regions evaluated by Alberta Stroke Program Early CT Score (ASPECTS) in 14 patients with acute middle cerebral artery stroke who had undergone whole-brain CTP using 320-row area detector CT was performed. Four radiologists reviewed EIC on NCCT, CTP-CBV, and tMIP in each ASPECTS region at onset using the continuous certainty factor method. Receiver operating characteristic analysis was performed to compare the relative performance for detection of EIC. The correlations were evaluated. tMIP-color showed the best discriminative value for detection of EIC. There were significant differences in the area under the curve for NCCT and tMIP-color, CTP-CBV (P < .05). Scatter plots of ASPECTS showed a positive significant correlation between NCCT, tMIP-gray, tMIP-color, and the follow-up study (NCCT, r = 0.32, P = .0166; tMIP-gray, r = 0.44, P = .0007; tMIP-color, r = 0.34, P = .0104). Because tMIP provides a high contrast parenchymal image with anatomical and vascular information in 1 sequential scan, it showed greater accuracy for detection of EIC and predicted the final infarct extent more accurately than NCCT based on ASPECTS.

AB - Noncontrast computed tomography (NCCT) has been used for the detection of early ischemic change (EIC); however, correct interpretation of NCCT findings requires much clinical experience. This study aimed to assess the accuracy of time maximum intensity projection computed tomography technique (tMIP), which reflects the maximum value for the time phase direction from the dynamic volume data for each projected plane, for detection of EIC, against that of NCCT. Retrospective review of NCCT, cerebral blood volume in CT perfusion (CTP-CBV), and tMIP of 186 lesions from 280 regions evaluated by Alberta Stroke Program Early CT Score (ASPECTS) in 14 patients with acute middle cerebral artery stroke who had undergone whole-brain CTP using 320-row area detector CT was performed. Four radiologists reviewed EIC on NCCT, CTP-CBV, and tMIP in each ASPECTS region at onset using the continuous certainty factor method. Receiver operating characteristic analysis was performed to compare the relative performance for detection of EIC. The correlations were evaluated. tMIP-color showed the best discriminative value for detection of EIC. There were significant differences in the area under the curve for NCCT and tMIP-color, CTP-CBV (P < .05). Scatter plots of ASPECTS showed a positive significant correlation between NCCT, tMIP-gray, tMIP-color, and the follow-up study (NCCT, r = 0.32, P = .0166; tMIP-gray, r = 0.44, P = .0007; tMIP-color, r = 0.34, P = .0104). Because tMIP provides a high contrast parenchymal image with anatomical and vascular information in 1 sequential scan, it showed greater accuracy for detection of EIC and predicted the final infarct extent more accurately than NCCT based on ASPECTS.

UR - http://www.scopus.com/inward/record.url?scp=85043280931&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85043280931&partnerID=8YFLogxK

U2 - 10.1097/MD.0000000000009906

DO - 10.1097/MD.0000000000009906

M3 - Article

C2 - 29489691

AN - SCOPUS:85043280931

VL - 97

JO - Medicine (United States)

JF - Medicine (United States)

SN - 0025-7974

IS - 9

M1 - e9906

ER -