Prevalence and distribution of Helicobacter pylori in the stomach of patients by upper gastrointestinal endoscopy

T. Shibata, I. Imoto, S. Takaji, T. Shima

Research output: Contribution to journalArticlepeer-review

Abstract

The prevalence of H. pylori colonization in the antrum and body was examined in patients with gastritis, duodenal ulcer (DU) and gastric ulcer (GU). The total prevalence was 63.5%, 90.0% and 85.5%, respectively. In patients with gastritis and DU, the frequency was similar at both sites, while in GU patients H. pylori positivity was increased markedly in the body compared with the antrum. Furthermore, in patients with antral and angular ulcers, biopsy studies from 8 different sites showed that the H. pylori density score was significantly higher at the ulcer sites than at the non-ulcer sites. H. pylori infection is strongly implicated in the pathogenesis of gastritis and peptic ulceration.

Original languageEnglish
Pages (from-to)3205-3209
Number of pages5
JournalNippon rinsho. Japanese journal of clinical medicine
Volume51
Issue number12
Publication statusPublished - 12-1993
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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