Prevalence and risk factors for epiretinal membranes in a Japanese population: The Hisayama study

Miho Miyazaki, Hidetoshi Nakamura, Michiaki Kubo, Yutaka Kiyohara, Mitsuo Iida, Tatsuro Ishibashi, Yoshiaki Nose

Research output: Contribution to journalArticle

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Abstract

Purpose: To examine the prevalence and risk factors for epiretinal membranes (ERMs) in a sample Japanese population. Methods: In 1998 a cross-sectional community survey was conducted among residents of Hisayama. A total of 688 men and 1087 women living in Hisayama, Japan, aged 40 years or older consented to participate in the study. Each participant underwent a comprehensive physical examination that included an ophthalmic examination. The presence of ERMs was judged from grading based on fundus examination using indirect ophthalmoscopy, slit lamp examination, and color fundus photographs. This study used non-stereoscopic 45° fundus photographs to grade ERMs, whereas the other population-based studies used 30° stereoscopic fundus photographs, which might explain some differences in prevalence of ERMs. Multiple logistic regression analysis was performed on the cross-sectional data to determine the risk factors for ERMs. The following ten possible risk factors were used: age; gender; hypertension; diabetes; serum cholesterol; serum HDL cholesterol; serum triglycerides; smoking habits; alcohol intake; and body mass index. Results: The prevalence of ERMs was 4.0%, and increased with age. The ERMs were more prevalent in women (4.3%) than in men (3.5%). Multiple logistic regression analysis showed that age and serum cholesterol significantly associated with ERMs. Conclusions: This study suggests that ERMs are less common in the Japanese population than in similar populations in Western countries, and that hypercholesterolemia is a relevant risk factor for ERMs.

Original languageEnglish
Pages (from-to)642-646
Number of pages5
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume241
Issue number8
DOIs
Publication statusPublished - 01-08-2003

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Epiretinal Membrane
Population
Serum
Logistic Models
Cholesterol
Regression Analysis
Ophthalmoscopy
Hypercholesterolemia
HDL Cholesterol
Physical Examination
Habits
Japan
Triglycerides
Body Mass Index
Color
Cross-Sectional Studies
Smoking
Alcohols

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Miyazaki, Miho ; Nakamura, Hidetoshi ; Kubo, Michiaki ; Kiyohara, Yutaka ; Iida, Mitsuo ; Ishibashi, Tatsuro ; Nose, Yoshiaki. / Prevalence and risk factors for epiretinal membranes in a Japanese population : The Hisayama study. In: Graefe's Archive for Clinical and Experimental Ophthalmology. 2003 ; Vol. 241, No. 8. pp. 642-646.
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abstract = "Purpose: To examine the prevalence and risk factors for epiretinal membranes (ERMs) in a sample Japanese population. Methods: In 1998 a cross-sectional community survey was conducted among residents of Hisayama. A total of 688 men and 1087 women living in Hisayama, Japan, aged 40 years or older consented to participate in the study. Each participant underwent a comprehensive physical examination that included an ophthalmic examination. The presence of ERMs was judged from grading based on fundus examination using indirect ophthalmoscopy, slit lamp examination, and color fundus photographs. This study used non-stereoscopic 45° fundus photographs to grade ERMs, whereas the other population-based studies used 30° stereoscopic fundus photographs, which might explain some differences in prevalence of ERMs. Multiple logistic regression analysis was performed on the cross-sectional data to determine the risk factors for ERMs. The following ten possible risk factors were used: age; gender; hypertension; diabetes; serum cholesterol; serum HDL cholesterol; serum triglycerides; smoking habits; alcohol intake; and body mass index. Results: The prevalence of ERMs was 4.0{\%}, and increased with age. The ERMs were more prevalent in women (4.3{\%}) than in men (3.5{\%}). Multiple logistic regression analysis showed that age and serum cholesterol significantly associated with ERMs. Conclusions: This study suggests that ERMs are less common in the Japanese population than in similar populations in Western countries, and that hypercholesterolemia is a relevant risk factor for ERMs.",
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Prevalence and risk factors for epiretinal membranes in a Japanese population : The Hisayama study. / Miyazaki, Miho; Nakamura, Hidetoshi; Kubo, Michiaki; Kiyohara, Yutaka; Iida, Mitsuo; Ishibashi, Tatsuro; Nose, Yoshiaki.

In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 241, No. 8, 01.08.2003, p. 642-646.

Research output: Contribution to journalArticle

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T1 - Prevalence and risk factors for epiretinal membranes in a Japanese population

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AU - Miyazaki, Miho

AU - Nakamura, Hidetoshi

AU - Kubo, Michiaki

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