The patient was a 72-year-old man who visited our hospital because of anemia. CT revealed a 10-cm enhanced mass lesion in the ascending colon. Colonoscopy confirmed a submucosal tumor in the ascending colon, in which erosion was found in the mucosa. Biopsy was attempted, but the tumor cell was not found. Bleeding from the submucosal tumor was considered to be the cause of anemia, therefore right hemicolectomy was performed. Although the tumor was not exposed to the serosa, it was difficult to dissect the ascending colon and retroperitoneum because of inflammation. The resected specimen was approximately 10x8 cm, and was considered to be a pedunculated submucosal tumor. Pathologic examination revealed primary liposarcoma which originated from the ascending colon. The patient received no postoperative therapy, and no recurrences have been observed 24 months after surgery.
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