Probable Lymphocytic Hypophysitis Diagnosed by Short-term Serial Computed Tomography and Gallium-67 Scintigraphy: —Case Report—

Hideki Murakami, Yuichi Hirose, Masachika Sagoh, Takuro Hayashi

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A 61-year-old female presented with headache, malaise, and left oculomotor nerve paralysis. Computed tomography (CT) demonstrated a diffuse pituitary mass and enlarged pituitary stalk with homogeneous contrast enhancement. Her symptoms gradually resolved without treatment. Gallium-67 scintigraphy showed abnormal uptake in the pituitary lesion. Serial CT every 2 weeks after admission showed homogeneous contrast enhancement and shrinking of the pituitary mass to a normal size 12 weeks after the onset. The final diagnosis was lymphocytic adenohypophysitis without biopsy. Recurrence has not been observed for 8 years after discharge. The patient did not need hormone replacement therapy. Histological examination is not always necessary to diagnose probable lymphocytic adenohypophysitis with the characteristic feature of rapid onset, abnormal gallium-67 uptake in the lesion, and resolution of symptoms in the acute stage with shrinking of the lesion on neuroimaging.

Original languageEnglish
Pages (from-to)174-178
Number of pages5
JournalNeurologia medico-chirurgica
Issue number2
Publication statusPublished - 01-01-1999


All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

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