TY - JOUR
T1 - Problems In The Treatment Of Postoperative Infections Following Abdominal Surgery
T2 - With Special Reference To Cases After Prophylaxis With Third-Generation Cephalosporins
AU - Shinagawa, Nagao
AU - Fukui, Takuji
AU - Suzuki, Tatsuya
AU - Hori, Keiichi
AU - Ogino, Kenji
AU - Mashita, Keiji
AU - Mizuno, Akira
AU - Takaoka, Tetsuro
AU - Mizuno, Isamu
AU - Yura, Jiro
PY - 1987
Y1 - 1987
N2 - The cephalosporin group of antimicrobials has gained general acceptance for surgical prophylaxis. However, the number and variety of cephalosporins now available have complicated the process of choosing the most effective agent. In our previous studies we produced evidence that third-generation cephalosporins resulted in postoperative infection rates lower than with second-generation cephalosporins. In this study, clinical isolates from patients with postoperative infections after prophylaxis with second- or third-generation cephalosporins were sensitive mainly to penicillins and/or aminoglycosides. There were no problems in the treatment of postoperative infections following abdominal surgery after prophylaxis with third-generation cephalosporins. It is advisable, however, that the newer antibiotics should not be given for prophylaxis, but reserved for the treatment of postoperative infections.
AB - The cephalosporin group of antimicrobials has gained general acceptance for surgical prophylaxis. However, the number and variety of cephalosporins now available have complicated the process of choosing the most effective agent. In our previous studies we produced evidence that third-generation cephalosporins resulted in postoperative infection rates lower than with second-generation cephalosporins. In this study, clinical isolates from patients with postoperative infections after prophylaxis with second- or third-generation cephalosporins were sensitive mainly to penicillins and/or aminoglycosides. There were no problems in the treatment of postoperative infections following abdominal surgery after prophylaxis with third-generation cephalosporins. It is advisable, however, that the newer antibiotics should not be given for prophylaxis, but reserved for the treatment of postoperative infections.
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U2 - 10.11250/chemotherapy1953.35.768
DO - 10.11250/chemotherapy1953.35.768
M3 - Article
AN - SCOPUS:85007851398
SN - 0009-3165
VL - 35
SP - 768
EP - 773
JO - CHEMOTHERAPY
JF - CHEMOTHERAPY
IS - 10
ER -
