TY - JOUR
T1 - Prognostic factors and a new preliminary scoring system for remission of type 2 diabetes mellitus after laparoscopic sleeve gastrectomy
AU - Umemura, Akira
AU - Sasaki, Akira
AU - Nitta, Hiroyuki
AU - Nikai, Haruka
AU - Baba, Shigeaki
AU - Takahara, Takeshi
AU - Hasegawa, Yasushi
AU - Katagiri, Hirokatsu
AU - Kanno, Shoji
AU - Ishigaki, Yasushi
N1 - Publisher Copyright:
© 2020, Springer Nature Singapore Pte Ltd.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Purpose: To evaluate the early remission rate of type 2 diabetes mellitus (T2DM) after laparoscopic sleeve gastrectomy (LSG) and establish a preliminary scoring system that predicts T2DM remission. Methods: We assessed the outcomes of 49 morbidly obese patients with T2DM who underwent LSG between 2008 and 2018. The prognostic factors for T2DM remission 1 year post-LSG were identified and an original scoring system was established. We validated our scoring system by comparing it with the individualized metabolic surgery score and the ABCD score. Results: The patients’ mean body weight loss and percentage of excess weight loss were 34.4 kg and 59.4%, respectively, while the T2DM remission rate was 77.5%. The serum insulin level and the T2DM duration were independent predictive factors, the receiver-operating characteristic (ROC) curves for which revealed cutoff values of 12.7 ng/mL and 72 months, respectively. We set our system’s score range at 0–2, whereby patients with higher scores have a good T2DM remission prognosis, as higher insulin levels, and/or shorter T2DM duration. Our scoring system had accuracy levels similar to those of the ABCD score with a simple stratification. Conclusion: Our preliminary scoring system attains a good level of accuracy for predicting T2DM remission.
AB - Purpose: To evaluate the early remission rate of type 2 diabetes mellitus (T2DM) after laparoscopic sleeve gastrectomy (LSG) and establish a preliminary scoring system that predicts T2DM remission. Methods: We assessed the outcomes of 49 morbidly obese patients with T2DM who underwent LSG between 2008 and 2018. The prognostic factors for T2DM remission 1 year post-LSG were identified and an original scoring system was established. We validated our scoring system by comparing it with the individualized metabolic surgery score and the ABCD score. Results: The patients’ mean body weight loss and percentage of excess weight loss were 34.4 kg and 59.4%, respectively, while the T2DM remission rate was 77.5%. The serum insulin level and the T2DM duration were independent predictive factors, the receiver-operating characteristic (ROC) curves for which revealed cutoff values of 12.7 ng/mL and 72 months, respectively. We set our system’s score range at 0–2, whereby patients with higher scores have a good T2DM remission prognosis, as higher insulin levels, and/or shorter T2DM duration. Our scoring system had accuracy levels similar to those of the ABCD score with a simple stratification. Conclusion: Our preliminary scoring system attains a good level of accuracy for predicting T2DM remission.
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U2 - 10.1007/s00595-020-01990-z
DO - 10.1007/s00595-020-01990-z
M3 - Article
C2 - 32170427
AN - SCOPUS:85081729349
SN - 0941-1291
VL - 50
SP - 1056
EP - 1064
JO - Surgery Today
JF - Surgery Today
IS - 9
ER -