TY - JOUR
T1 - Properties of membrane phospholipids and their fatty acyl compositions of secretory granules from rat parotid gland
AU - Mizuno, M.
AU - Kameyama, Y.
AU - Yashiro, K.
AU - Yokota, Y.
N1 - Funding Information:
ACKNOWLEDGMENT We thank Mr. Akihiko Okada and Mrs. Teruyo Tanahashi for their helpful assistances. This study was supported in part by Grant-in-Aid for Scientific Research from the Ministry of Education, Culture and Science, Japan and a grant from the Miyata Science Research Foundation of Asahi University.
PY - 1987/9
Y1 - 1987/9
N2 - A secretory granular fraction isolated from rat parotid glands was remarkably different from a microsomal fraction in its phospholipid composition. It had higher levels of lysophospholipids (8%) and phosphatidylethanolamine (31%), while there were lower levels of phosphatidylcholine (40%) and phosphatidylserine (2.1%) than the microsomal fraction. However, fatty acid compositions of individual phospholipid classes from the two subfractions were found to be nearly similar to each other. ESR analysis demonstrated that extracted phospholipids from the secretory granular fraction were more fluid than those from microsomes. The relevance of these observations to physiological function of secretory granules is discussed.
AB - A secretory granular fraction isolated from rat parotid glands was remarkably different from a microsomal fraction in its phospholipid composition. It had higher levels of lysophospholipids (8%) and phosphatidylethanolamine (31%), while there were lower levels of phosphatidylcholine (40%) and phosphatidylserine (2.1%) than the microsomal fraction. However, fatty acid compositions of individual phospholipid classes from the two subfractions were found to be nearly similar to each other. ESR analysis demonstrated that extracted phospholipids from the secretory granular fraction were more fluid than those from microsomes. The relevance of these observations to physiological function of secretory granules is discussed.
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U2 - 10.1016/0309-1651(87)90096-8
DO - 10.1016/0309-1651(87)90096-8
M3 - Article
C2 - 2445495
AN - SCOPUS:0023405914
SN - 0309-1651
VL - 11
SP - 629
EP - 636
JO - Cell Biology International Reports
JF - Cell Biology International Reports
IS - 9
ER -